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From a recombinant key antigen to an accurate, affordable serological test: Lessons learnt from COVID-19 for future pandemics.
Alvim RGF, Lima TM, Rodrigues DAS, Marsili FF, Bozza VBT, Higa LM, Monteiro FL, Abreu DPB, Leitão IC, Carvalho RS, Galliez RM, Castineiras TMPP, Travassos LH, Nobrega A, Tanuri A, Ferreira OC Jr, Vale AM, Castilho LR. Alvim RGF, et al. Among authors: travassos lh. Biochem Eng J. 2022 Aug;186:108537. doi: 10.1016/j.bej.2022.108537. Epub 2022 Jul 16. Biochem Eng J. 2022. PMID: 35874089 Free PMC article.
Protein aggregation as a cellular response to oxidative stress induced by heme and iron.
Vasconcellos LR, Dutra FF, Siqueira MS, Paula-Neto HA, Dahan J, Kiarely E, Carneiro LA, Bozza MT, Travassos LH. Vasconcellos LR, et al. Among authors: travassos lh. Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7474-E7482. doi: 10.1073/pnas.1608928113. Epub 2016 Nov 7. Proc Natl Acad Sci U S A. 2016. PMID: 27821769 Free PMC article.
Heme Oxygenase-1 and Autophagy Linked for Cytoprotection.
Vasconcellos LR, Siqueira MS, Moraes R, Carneiro LA, Bozza MT, Travassos LH. Vasconcellos LR, et al. Among authors: travassos lh. Curr Pharm Des. 2018;24(20):2311-2316. doi: 10.2174/1381612824666180727100909. Curr Pharm Des. 2018. PMID: 30051776 Review.
Heme and iron induce protein aggregation.
Travassos LH, Vasconcellos LR, Bozza MT, Carneiro LA. Travassos LH, et al. Autophagy. 2017 Mar 4;13(3):625-626. doi: 10.1080/15548627.2016.1271515. Epub 2017 Jan 5. Autophagy. 2017. PMID: 28055290 Free PMC article.
Heme amplifies the innate immune response to microbial molecules through spleen tyrosine kinase (Syk)-dependent reactive oxygen species generation.
Fernandez PL, Dutra FF, Alves L, Figueiredo RT, Mourão-Sa D, Fortes GB, Bergstrand S, Lönn D, Cevallos RR, Pereira RMS, Lopes UG, Travassos LH, Paiva CN, Bozza MT. Fernandez PL, et al. Among authors: travassos lh. J Biol Chem. 2010 Oct 22;285(43):32844-32851. doi: 10.1074/jbc.M110.146076. Epub 2010 Aug 20. J Biol Chem. 2010. PMID: 20729208 Free PMC article.
45 results