Meiering EM - Search Results

1

Immature ALS-associated mutant superoxide dismutases form variable aggregate structures through distinct oligomerization processes.

Deol HK, Broom HR, Siebeneichler B, Lee B, Leonenko Z, Meiering EM. Deol HK, et al. Among authors: meiering em. Biophys Chem. 2022 Sep;288:106844. doi: 10.1016/j.bpc.2022.106844. Epub 2022 Jun 9. Biophys Chem. 2022. PMID: 35872467

2

Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis show enhanced formation of aggregates in vitro.

Stathopulos PB, Rumfeldt JA, Scholz GA, Irani RA, Frey HE, Hallewell RA, Lepock JR, Meiering EM. Stathopulos PB, et al. Among authors: meiering em. Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7021-6. doi: 10.1073/pnas.1237797100. Epub 2003 May 28. Proc Natl Acad Sci U S A. 2003. PMID: 12773627 Free PMC article.

3

Mechanism and thermodynamics of guanidinium chloride-induced denaturation of ALS-associated mutant Cu,Zn superoxide dismutases.

Rumfeldt JA, Stathopulos PB, Chakrabarrty A, Lepock JR, Meiering EM. Rumfeldt JA, et al. Among authors: meiering em. J Mol Biol. 2006 Jan 6;355(1):106-23. doi: 10.1016/j.jmb.2005.10.042. Epub 2005 Nov 8. J Mol Biol. 2006. PMID: 16307756

4

Calorimetric analysis of thermodynamic stability and aggregation for apo and holo amyotrophic lateral sclerosis-associated Gly-93 mutants of superoxide dismutase.

Stathopulos PB, Rumfeldt JA, Karbassi F, Siddall CA, Lepock JR, Meiering EM. Stathopulos PB, et al. Among authors: meiering em. J Biol Chem. 2006 Mar 10;281(10):6184-93. doi: 10.1074/jbc.M509496200. Epub 2006 Jan 3. J Biol Chem. 2006. PMID: 16407238 Free article.

5

Equilibrium thermodynamic analysis of amyotrophic lateral sclerosis-associated mutant apo Cu,Zn superoxide dismutases.

Vassall KA, Stathopulos PB, Rumfeldt JA, Lepock JR, Meiering EM. Vassall KA, et al. Among authors: meiering em. Biochemistry. 2006 Jun 13;45(23):7366-79. doi: 10.1021/bi0600953. Biochemistry. 2006. PMID: 16752926

6

Unfolding and folding kinetics of amyotrophic lateral sclerosis-associated mutant Cu,Zn superoxide dismutases.

Rumfeldt JA, Lepock JR, Meiering EM. Rumfeldt JA, et al. Among authors: meiering em. J Mol Biol. 2009 Jan 9;385(1):278-98. doi: 10.1016/j.jmb.2008.10.003. Epub 2008 Oct 11. J Mol Biol. 2009. PMID: 18951903

7

Nonamyloid aggregates arising from mature copper/zinc superoxide dismutases resemble those observed in amyotrophic lateral sclerosis.

Hwang YM, Stathopulos PB, Dimmick K, Yang H, Badiei HR, Tong MS, Rumfeldt JA, Chen P, Karanassios V, Meiering EM. Hwang YM, et al. Among authors: meiering em. J Biol Chem. 2010 Dec 31;285(53):41701-11. doi: 10.1074/jbc.M110.113696. Epub 2010 Oct 25. J Biol Chem. 2010. PMID: 20974846 Free PMC article.

8

Decreased stability and increased formation of soluble aggregates by immature superoxide dismutase do not account for disease severity in ALS.

Vassall KA, Stubbs HR, Primmer HA, Tong MS, Sullivan SM, Sobering R, Srinivasan S, Briere LA, Dunn SD, Colón W, Meiering EM. Vassall KA, et al. Among authors: meiering em. Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2210-5. doi: 10.1073/pnas.0913021108. Epub 2011 Jan 21. Proc Natl Acad Sci U S A. 2011. PMID: 21257910 Free PMC article.

9

Energetics of oligomeric protein folding and association.

Doyle CM, Rumfeldt JA, Broom HR, Broom A, Stathopulos PB, Vassall KA, Almey JJ, Meiering EM. Doyle CM, et al. Among authors: meiering em. Arch Biochem Biophys. 2013 Mar;531(1-2):44-64. doi: 10.1016/j.abb.2012.12.005. Epub 2012 Dec 13. Arch Biochem Biophys. 2013. PMID: 23246784 Review.

10

Many roads lead to Rome? Multiple modes of Cu,Zn superoxide dismutase destabilization, misfolding and aggregation in amyotrophic lateral sclerosis.

Broom HR, Rumfeldt JA, Meiering EM. Broom HR, et al. Among authors: meiering em. Essays Biochem. 2014;56:149-65. doi: 10.1042/bse0560149. Essays Biochem. 2014. PMID: 25131593

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