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SARS-CoV-2 spike protein inhibits megalin-mediated albumin endocytosis in proximal tubule epithelial cells.
Biochim Biophys Acta Mol Basis Dis. 2022 Dec 1;1868(12):166496. doi: 10.1016/j.bbadis.2022.166496. Epub 2022 Jul 18.
Biochim Biophys Acta Mol Basis Dis. 2022.
PMID: 35863591
Free PMC article.
Surface megalin expression is a target to the inhibitory effect of bradykinin on the renal albumin endocytosis.
Alves SAS, Florentino LS, Teixeira DE, Silva-Aguiar RP, Peruchetti DB, Oliveira AC, Scharfstein J, Marzolo MP, Pinheiro AAS, Caruso-Neves C.
Alves SAS, et al. Among authors: florentino ls.
Peptides. 2021 Dec;146:170646. doi: 10.1016/j.peptides.2021.170646. Epub 2021 Sep 6.
Peptides. 2021.
PMID: 34500007
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Albumin Expands Albumin Reabsorption Capacity in Proximal Tubule Epithelial Cells through a Positive Feedback Loop between AKT and Megalin.
Silva-Aguiar RP, Peruchetti DB, Florentino LS, Takiya CM, Marzolo MP, Dias WB, Pinheiro AAS, Caruso-Neves C.
Silva-Aguiar RP, et al. Among authors: florentino ls.
Int J Mol Sci. 2022 Jan 13;23(2):848. doi: 10.3390/ijms23020848.
Int J Mol Sci. 2022.
PMID: 35055044
Free PMC article.
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