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A family of NADPH/NADP+ biosensors reveals in vivo dynamics of central redox metabolism across eukaryotes.
Scherschel M, Niemeier JO, Jacobs LJHC, Hoffmann MDA, Diederich A, Bell C, Höhne P, Raetz S, Kroll JB, Steinbeck J, Lichtenauer S, Multhoff J, Zimmermann J, Sadhanasatish T, Rothemann RA, Grashoff C, Messens J, Ampofo E, Laschke MW, Riemer J, Roma LP, Schwarzländer M, Morgan B. Scherschel M, et al. Among authors: rothemann ra. Nat Commun. 2024 Dec 19;15(1):10704. doi: 10.1038/s41467-024-55302-x. Nat Commun. 2024. PMID: 39702652 Free PMC article.
AIFM1 is a component of the mitochondrial disulfide relay that drives complex I assembly through efficient import of NDUFS5.
Salscheider SL, Gerlich S, Cabrera-Orefice A, Peker E, Rothemann RA, Murschall LM, Finger Y, Szczepanowska K, Ahmadi ZA, Guerrero-Castillo S, Erdogan A, Becker M, Ali M, Habich M, Petrungaro C, Burdina N, Schwarz G, Klußmann M, Neundorf I, Stroud DA, Ryan MT, Trifunovic A, Brandt U, Riemer J. Salscheider SL, et al. Among authors: rothemann ra. EMBO J. 2022 Sep 1;41(17):e110784. doi: 10.15252/embj.2022110784. Epub 2022 Jul 20. EMBO J. 2022. PMID: 35859387 Free PMC article.