Frankel WN - Search Results

1

Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex.

Wu X, Sosunov AA, Lado W, Teoh JJ, Ham A, Li H, Al-Dalahmah O, Gill BJA, Arancio O, Schevon CA, Frankel WN, McKhann GM 2nd, Sulzer D, Goldman JE, Tang G. Wu X, et al. Among authors: frankel wn. Cell Rep. 2022 Jul 19;40(3):111085. doi: 10.1016/j.celrep.2022.111085. Cell Rep. 2022. PMID: 35858542 Free PMC article.

2

Single unit analysis and wide-field imaging reveal alterations in excitatory and inhibitory neurons in glioma.

Gill BJA, Khan FA, Goldberg AR, Merricks EM, Wu X, Sosunov AA, Sudhakar TD, Dovas A, Lado W, Michalak AJ, Teoh JJ, Liou JY, Frankel WN, McKhann GM, Canoll P, Schevon CA. Gill BJA, et al. Among authors: frankel wn. Brain. 2022 Oct 21;145(10):3666-3680. doi: 10.1093/brain/awac168. Brain. 2022. PMID: 35552612 Free PMC article.

3

RNAi-Based Gene Therapy Rescues Developmental and Epileptic Encephalopathy in a Genetic Mouse Model.

Aimiuwu OV, Fowler AM, Sah M, Teoh JJ, Kanber A, Pyne NK, Petri S, Rosenthal-Weiss C, Yang M, Harper SQ, Frankel WN. Aimiuwu OV, et al. Among authors: frankel wn. Mol Ther. 2020 Jul 8;28(7):1706-1716. doi: 10.1016/j.ymthe.2020.04.007. Epub 2020 Apr 16. Mol Ther. 2020. PMID: 32353324 Free PMC article.

4

Reduced GABAergic Neuron Excitability, Altered Synaptic Connectivity, and Seizures in a KCNT1 Gain-of-Function Mouse Model of Childhood Epilepsy.

Shore AN, Colombo S, Tobin WF, Petri S, Cullen ER, Dominguez S, Bostick CD, Beaumont MA, Williams D, Khodagholy D, Yang M, Lutz CM, Peng Y, Gelinas JN, Goldstein DB, Boland MJ, Frankel WN, Weston MC. Shore AN, et al. Among authors: frankel wn. Cell Rep. 2020 Oct 27;33(4):108303. doi: 10.1016/j.celrep.2020.108303. Cell Rep. 2020. PMID: 33113364 Free PMC article.

5

Expression of the Neuronal tRNA n-Tr20 Regulates Synaptic Transmission and Seizure Susceptibility.

Kapur M, Ganguly A, Nagy G, Adamson SI, Chuang JH, Frankel WN, Ackerman SL. Kapur M, et al. Among authors: frankel wn. Neuron. 2020 Oct 14;108(1):193-208.e9. doi: 10.1016/j.neuron.2020.07.023. Epub 2020 Aug 26. Neuron. 2020. PMID: 32853550 Free PMC article.

6

Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABA_A receptors.

Teoh J, Subramanian N, Pero ME, Bartolini F, Amador A, Kanber A, Williams D, Petri S, Yang M, Allen AS, Beal J, Haut SR, Frankel WN. Teoh J, et al. Among authors: frankel wn. Neurobiol Dis. 2020 Feb;134:104632. doi: 10.1016/j.nbd.2019.104632. Epub 2019 Oct 31. Neurobiol Dis. 2020. PMID: 31678406 Free PMC article.

7

Altered Fast Synaptic Transmission in a Mouse Model of DNM1-Associated Developmental Epileptic Encephalopathy.

McCabe MP, Shore AN, Frankel WN, Weston MC. McCabe MP, et al. Among authors: frankel wn. eNeuro. 2021 Mar 10;8(2):ENEURO.0269-20.2020. doi: 10.1523/ENEURO.0269-20.2020. Print 2021 Mar-Apr. eNeuro. 2021. PMID: 33372033 Free PMC article.

8

Altered excitatory transmission onto hippocampal interneurons in the IQSEC2 mouse model of X-linked neurodevelopmental disease.

Sah M, Shore AN, Petri S, Kanber A, Yang M, Weston MC, Frankel WN. Sah M, et al. Among authors: frankel wn. Neurobiol Dis. 2020 Apr;137:104758. doi: 10.1016/j.nbd.2020.104758. Epub 2020 Jan 21. Neurobiol Dis. 2020. PMID: 31978606 Free PMC article.

9

Overlaps, gaps, and complexities of mouse models of Developmental and Epileptic Encephalopathy.

Wang W, Frankel WN. Wang W, et al. Among authors: frankel wn. Neurobiol Dis. 2021 Jan;148:105220. doi: 10.1016/j.nbd.2020.105220. Epub 2020 Dec 7. Neurobiol Dis. 2021. PMID: 33301879 Free PMC article. Review.

10

Inhibition of microRNA 128 promotes excitability of cultured cortical neuronal networks.

McSweeney KM, Gussow AB, Bradrick SS, Dugger SA, Gelfman S, Wang Q, Petrovski S, Frankel WN, Boland MJ, Goldstein DB. McSweeney KM, et al. Among authors: frankel wn. Genome Res. 2016 Oct;26(10):1411-1416. doi: 10.1101/gr.199828.115. Epub 2016 Aug 11. Genome Res. 2016. PMID: 27516621 Free PMC article.

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