Ramanujan S - Search Results

1

Integrated systems modeling of severe asthma: Exploration of IL-33/ST2 antagonism.

Gadkar K, Feigelman J, Sukumaran S, Rodrigo MC, Staton T, Cai F, Bauer RN, Choy DF, Stokes CL, Scheerens H, Ramanujan S. Gadkar K, et al. Among authors: ramanujan s. CPT Pharmacometrics Syst Pharmacol. 2022 Sep;11(9):1268-1277. doi: 10.1002/psp4.12842. Epub 2022 Jul 20. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35857704 Free PMC article.

2

Mechanisms mediating anti-CD3 antibody efficacy: insights from a mathematical model of type 1 diabetes.

Young DL, Ramanujan S, Kreuwel HT, Whiting CC, Gadkar KG, Shoda LK. Young DL, et al. Among authors: ramanujan s. Ann N Y Acad Sci. 2006 Oct;1079:369-73. doi: 10.1196/annals.1375.057. Ann N Y Acad Sci. 2006. PMID: 17130581

3

The virtual NOD mouse: applying predictive biosimulation to research in type 1 diabetes.

Zheng Y, Kreuwel HT, Young DL, Shoda LK, Ramanujan S, Gadkar KG, Atkinson MA, Whiting CC. Zheng Y, et al. Among authors: ramanujan s. Ann N Y Acad Sci. 2007 Apr;1103:45-62. doi: 10.1196/annals.1394.014. Epub 2007 Mar 21. Ann N Y Acad Sci. 2007. PMID: 17376834

4

Dosing and timing effects of anti-CD40L therapy: predictions from a mathematical model of type 1 diabetes.

Gadkar KG, Shoda LK, Kreuwel HT, Ramanujan S, Zheng Y, Whiting CC, Young DL. Gadkar KG, et al. Among authors: ramanujan s. Ann N Y Acad Sci. 2007 Apr;1103:63-8. doi: 10.1196/annals.1394.013. Epub 2007 Mar 21. Ann N Y Acad Sci. 2007. PMID: 17376835

5

A Mechanistic Systems Pharmacology Model for Prediction of LDL Cholesterol Lowering by PCSK9 Antagonism in Human Dyslipidemic Populations.

Gadkar K, Budha N, Baruch A, Davis JD, Fielder P, Ramanujan S. Gadkar K, et al. Among authors: ramanujan s. CPT Pharmacometrics Syst Pharmacol. 2014 Nov 26;3(11):e149. doi: 10.1038/psp.2014.47. CPT Pharmacometrics Syst Pharmacol. 2014. PMID: 25426564 Free PMC article.

6

Mechanism-Based Pharmacokinetic/Pharmacodynamic Model for THIOMAB™ Drug Conjugates.

Sukumaran S, Gadkar K, Zhang C, Bhakta S, Liu L, Xu K, Raab H, Yu SF, Mai E, Fourie-O'Donohue A, Kozak KR, Ramanujan S, Junutula JR, Lin K. Sukumaran S, et al. Among authors: ramanujan s. Pharm Res. 2015 Jun;32(6):1884-93. doi: 10.1007/s11095-014-1582-1. Epub 2014 Dec 2. Pharm Res. 2015. PMID: 25446772

7

Challenges and Opportunities for Quantitative Clinical Pharmacology in Cancer Immunotherapy: Something Old, Something New, Something Borrowed, and Something Blue.

Stroh M, Carlile DJ, Li CC, Wagg J, Ribba B, Ramanujan S, Jin J, Xu J, Charoin JE, Xhu ZX, Morcos PN, Davis JD, Phipps A. Stroh M, et al. Among authors: ramanujan s. CPT Pharmacometrics Syst Pharmacol. 2015 Sep;4(9):495-7. doi: 10.1002/psp4.12014. Epub 2015 Sep 11. CPT Pharmacometrics Syst Pharmacol. 2015. PMID: 26451328 Free PMC article.

8

Evaluation of HDL-modulating interventions for cardiovascular risk reduction using a systems pharmacology approach.

Gadkar K, Lu J, Sahasranaman S, Davis J, Mazer NA, Ramanujan S. Gadkar K, et al. Among authors: ramanujan s. J Lipid Res. 2016 Jan;57(1):46-55. doi: 10.1194/jlr.M057943. Epub 2015 Nov 1. J Lipid Res. 2016. PMID: 26522778 Free PMC article.

9

Mathematical PKPD and safety model of bispecific TfR/BACE1 antibodies for the optimization of antibody uptake in brain.

Gadkar K, Yadav DB, Zuchero JY, Couch JA, Kanodia J, Kenrick MK, Atwal JK, Dennis MS, Prabhu S, Watts RJ, Joseph SB, Ramanujan S. Gadkar K, et al. Among authors: ramanujan s. Eur J Pharm Biopharm. 2016 Apr;101:53-61. doi: 10.1016/j.ejpb.2016.01.009. Epub 2016 Jan 25. Eur J Pharm Biopharm. 2016. PMID: 26820920

10

A Six-Stage Workflow for Robust Application of Systems Pharmacology.

Gadkar K, Kirouac DC, Mager DE, van der Graaf PH, Ramanujan S. Gadkar K, et al. Among authors: ramanujan s. CPT Pharmacometrics Syst Pharmacol. 2016 May;5(5):235-49. doi: 10.1002/psp4.12071. Epub 2016 Apr 16. CPT Pharmacometrics Syst Pharmacol. 2016. PMID: 27299936 Free PMC article.

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