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Miswiring of Merkel cell and pruriceptive C fiber drives the itch-scratch cycle.
Feng J, Zhao Y, Xie Z, Zang K, Sviben S, Hu X, Fitzpatrick JAJ, Wen L, Liu Y, Wang T, Lawson K, Liu Q, Yan Y, Dong X, Han L, Wu GF, Kim BS, Hu H. Feng J, et al. Among authors: xie z. Sci Transl Med. 2022 Jul 13;14(653):eabn4819. doi: 10.1126/scitranslmed.abn4819. Epub 2022 Jul 13. Sci Transl Med. 2022. PMID: 35857641 Free PMC article.
TRP Channels as Drug Targets to Relieve Itch.
Xie Z, Hu H. Xie Z, et al. Pharmaceuticals (Basel). 2018 Oct 6;11(4):100. doi: 10.3390/ph11040100. Pharmaceuticals (Basel). 2018. PMID: 30301231 Free PMC article. Review.
Gating of human TRPV3 in a lipid bilayer.
Deng Z, Maksaev G, Rau M, Xie Z, Hu H, Fitzpatrick JAJ, Yuan P. Deng Z, et al. Among authors: xie z. Nat Struct Mol Biol. 2020 Jul;27(7):635-644. doi: 10.1038/s41594-020-0428-2. Epub 2020 Jun 22. Nat Struct Mol Biol. 2020. PMID: 32572252 Free PMC article.
A basophil-neuronal axis promotes itch.
Wang F, Trier AM, Li F, Kim S, Chen Z, Chai JN, Mack MR, Morrison SA, Hamilton JD, Baek J, Yang TB, Ver Heul AM, Xu AZ, Xie Z, Dong X, Kubo M, Hu H, Hsieh CS, Dong X, Liu Q, Margolis DJ, Ardeleanu M, Miller MJ, Kim BS. Wang F, et al. Among authors: xie z. Cell. 2021 Jan 21;184(2):422-440.e17. doi: 10.1016/j.cell.2020.12.033. Epub 2021 Jan 14. Cell. 2021. PMID: 33450207 Free PMC article.
Mechanisms of Broad-Band UVB Irradiation‒Induced Itch in Mice.
Cao L, Yue X, Zhao Y, Du L, Xie Z, Yuan Y, Zhang S, Li F, Feng J, Hu H. Cao L, et al. Among authors: xie z. J Invest Dermatol. 2021 Oct;141(10):2499-2508.e3. doi: 10.1016/j.jid.2021.03.015. Epub 2021 Apr 1. J Invest Dermatol. 2021. PMID: 33812858 Free PMC article.
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