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Pharmacogenetics-guided dalcetrapib therapy after an acute coronary syndrome: the dal-GenE trial.
Tardif JC, Pfeffer MA, Kouz S, Koenig W, Maggioni AP, McMurray JJV, Mooser V, Waters DD, Grégoire JC, L'Allier PL, Wouter Jukema J, White HD, Heinonen T, Black DM, Laghrissi-Thode F, Levesque S, Guertin MC, Dubé MP; dal-GenE Investigators. Tardif JC, et al. Among authors: black dm. Eur Heart J. 2022 Oct 14;43(39):3947-3956. doi: 10.1093/eurheartj/ehac374. Eur Heart J. 2022. PMID: 35856777 Free PMC article. Clinical Trial.
Study design of Dal-GenE, a pharmacogenetic trial targeting reduction of cardiovascular events with dalcetrapib.
Tardif JC, Dubé MP, Pfeffer MA, Waters DD, Koenig W, Maggioni AP, McMurray JJV, Mooser V, White HD, Heinonen T, Black DM, Guertin MC; dal-GenE Investigators. Tardif JC, et al. Among authors: black dm. Am Heart J. 2020 Apr;222:157-165. doi: 10.1016/j.ahj.2020.01.007. Epub 2020 Jan 17. Am Heart J. 2020. PMID: 32087417 Free article. Clinical Trial.
Role of Adenylate Cyclase 9 in the Pharmacogenomic Response to Dalcetrapib: Clinical Paradigm and Molecular Mechanisms in Precision Cardiovascular Medicine.
Rhainds D, Packard CJ, Brodeur MR, Niesor EJ, Sacks FM, Jukema JW, Wright RS, Waters DD, Heinonen T, Black DM, Laghrissi-Thode F, Dubé MP, Pfeffer MA, Tardif JC. Rhainds D, et al. Among authors: black dm. Circ Genom Precis Med. 2021 Apr;14(2):e003219. doi: 10.1161/CIRCGEN.121.003219. Epub 2021 Apr 2. Circ Genom Precis Med. 2021. PMID: 33794646 Free PMC article.
Clinical Pharmacokinetics and Pharmacodynamics of Dalcetrapib.
Black DM, Bentley D, Chapel S, Lee J, Briggs E, Heinonen T. Black DM, et al. Clin Pharmacokinet. 2018 Nov;57(11):1359-1367. doi: 10.1007/s40262-018-0656-3. Clin Pharmacokinet. 2018. PMID: 29730761 Free PMC article. Review.
Dalcetrapib Reduces Risk of New-Onset Diabetes in Patients With Coronary Heart Disease.
Schwartz GG, Leiter LA, Ballantyne CM, Barter PJ, Black DM, Kallend D, Laghrissi-Thode F, Leitersdorf E, McMurray JJV, Nicholls SJ, Olsson AG, Preiss D, Shah PK, Tardif JC, Kittelson J. Schwartz GG, et al. Among authors: black dm. Diabetes Care. 2020 May;43(5):1077-1084. doi: 10.2337/dc19-2204. Epub 2020 Mar 6. Diabetes Care. 2020. PMID: 32144166 Free PMC article. Clinical Trial.
Association of high-density lipoprotein particle concentration with cardiovascular risk following acute coronary syndrome: A case-cohort analysis of the dal-Outcomes trial.
Salahuddin T, Kittelson J, Tardif JC, Shah PK, Olsson AG, Nicholls SJ, Leitersdorf E, Leiter LA, Kallend D, Black DM, Barter PJ, Ballantyne CM, Schwartz GG. Salahuddin T, et al. Among authors: black dm. Am Heart J. 2020 Mar;221:60-66. doi: 10.1016/j.ahj.2019.12.003. Epub 2019 Dec 16. Am Heart J. 2020. PMID: 31927126
461 results