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Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus replication through blockage of membranous web formation.
Anggakusuma, Romero-Brey I, Berger C, Colpitts CC, Boldanova T, Engelmann M, Todt D, Perin PM, Behrendt P, Vondran FW, Xu S, Goffinet C, Schang LM, Heim MH, Bartenschlager R, Pietschmann T, Steinmann E. Anggakusuma, et al. Among authors: goffinet c. Hepatology. 2015 Sep;62(3):702-14. doi: 10.1002/hep.27913. Epub 2015 Jul 28. Hepatology. 2015. PMID: 25999047
COVID-19 severity correlates with airway epithelium-immune cell interactions identified by single-cell analysis.
Chua RL, Lukassen S, Trump S, Hennig BP, Wendisch D, Pott F, Debnath O, Thürmann L, Kurth F, Völker MT, Kazmierski J, Timmermann B, Twardziok S, Schneider S, Machleidt F, Müller-Redetzky H, Maier M, Krannich A, Schmidt S, Balzer F, Liebig J, Loske J, Suttorp N, Eils J, Ishaque N, Liebert UG, von Kalle C, Hocke A, Witzenrath M, Goffinet C, Drosten C, Laudi S, Lehmann I, Conrad C, Sander LE, Eils R. Chua RL, et al. Among authors: goffinet c. Nat Biotechnol. 2020 Aug;38(8):970-979. doi: 10.1038/s41587-020-0602-4. Epub 2020 Jun 26. Nat Biotechnol. 2020. PMID: 32591762
Absence of cGAS-mediated type I IFN responses in HIV-1-infected T cells.
Elsner C, Ponnurangam A, Kazmierski J, Zillinger T, Jansen J, Todt D, Döhner K, Xu S, Ducroux A, Kriedemann N, Malassa A, Larsen PK, Hartmann G, Barchet W, Steinmann E, Kalinke U, Sodeik B, Goffinet C. Elsner C, et al. Among authors: goffinet c. Proc Natl Acad Sci U S A. 2020 Aug 11;117(32):19475-19486. doi: 10.1073/pnas.2002481117. Epub 2020 Jul 24. Proc Natl Acad Sci U S A. 2020. PMID: 32709741 Free PMC article.
Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19.
Trump S, Lukassen S, Anker MS, Chua RL, Liebig J, Thürmann L, Corman VM, Binder M, Loske J, Klasa C, Krieger T, Hennig BP, Messingschlager M, Pott F, Kazmierski J, Twardziok S, Albrecht JP, Eils J, Hadzibegovic S, Lena A, Heidecker B, Bürgel T, Steinfeldt J, Goffinet C, Kurth F, Witzenrath M, Völker MT, Müller SD, Liebert UG, Ishaque N, Kaderali L, Sander LE, Drosten C, Laudi S, Eils R, Conrad C, Landmesser U, Lehmann I. Trump S, et al. Among authors: goffinet c. Nat Biotechnol. 2021 Jun;39(6):705-716. doi: 10.1038/s41587-020-00796-1. Epub 2020 Dec 24. Nat Biotechnol. 2021. PMID: 33361824
Interferon antagonism by SARS-CoV-2: a functional study using reverse genetics.
Schroeder S, Pott F, Niemeyer D, Veith T, Richter A, Muth D, Goffinet C, Müller MA, Drosten C. Schroeder S, et al. Among authors: goffinet c. Lancet Microbe. 2021 May;2(5):e210-e218. doi: 10.1016/S2666-5247(21)00027-6. Epub 2021 Mar 4. Lancet Microbe. 2021. PMID: 33969329 Free PMC article.
Human IFITM3 restricts chikungunya virus and Mayaro virus infection and is susceptible to virus-mediated counteraction.
Franz S, Pott F, Zillinger T, Schüler C, Dapa S, Fischer C, Passos V, Stenzel S, Chen F, Döhner K, Hartmann G, Sodeik B, Pessler F, Simmons G, Drexler JF, Goffinet C. Franz S, et al. Among authors: goffinet c. Life Sci Alliance. 2021 Jun 2;4(7):e202000909. doi: 10.26508/lsa.202000909. Print 2021 Jul. Life Sci Alliance. 2021. PMID: 34078739 Free PMC article.
82 results