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Comparison of actionable events detected in cancer genomes by whole-genome sequencing, in silico whole-exome and mutation panels.
Ramarao-Milne P, Kondrashova O, Patch AM, Nones K, Koufariotis LT, Newell F, Addala V, Lakis V, Holmes O, Leonard C, Wood S, Xu Q, Mukhopadhyay P, Naeini MM, Steinfort D, Williamson JP, Bint M, Pahoff C, Nguyen PT, Twaddell S, Arnold D, Grainge C, Basirzadeh F, Fielding D, Dalley AJ, Chittoory H, Simpson PT, Aoude LG, Bonazzi VF, Patel K, Barbour AP, Fennell DA, Robinson BW, Creaney J, Hollway G, Pearson JV, Waddell N. Ramarao-Milne P, et al. Among authors: aoude lg. ESMO Open. 2022 Aug;7(4):100540. doi: 10.1016/j.esmoop.2022.100540. Epub 2022 Jul 15. ESMO Open. 2022. PMID: 35849877 Free PMC article.
Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing.
Stark MS, Woods SL, Gartside MG, Bonazzi VF, Dutton-Regester K, Aoude LG, Chow D, Sereduk C, Niemi NM, Tang N, Ellis JJ, Reid J, Zismann V, Tyagi S, Muzny D, Newsham I, Wu Y, Palmer JM, Pollak T, Youngkin D, Brooks BR, Lanagan C, Schmidt CW, Kobe B, MacKeigan JP, Yin H, Brown KM, Gibbs R, Trent J, Hayward NK. Stark MS, et al. Among authors: aoude lg. Nat Genet. 2011 Dec 25;44(2):165-9. doi: 10.1038/ng.1041. Nat Genet. 2011. PMID: 22197930 Free PMC article.
Complex structural rearrangements are present in high-grade dysplastic Barrett's oesophagus samples.
Newell F, Patel K, Gartside M, Krause L, Brosda S, Aoude LG, Loffler KA, Bonazzi VF, Patch AM, Kazakoff SH, Holmes O, Xu Q, Wood S, Leonard C, Lampe G, Lord RV, Whiteman DC, Pearson JV, Nones K, Waddell N, Barbour AP. Newell F, et al. Among authors: aoude lg. BMC Med Genomics. 2019 Feb 4;12(1):31. doi: 10.1186/s12920-019-0476-9. BMC Med Genomics. 2019. PMID: 30717762 Free PMC article.
Radiomics Biomarkers Correlate with CD8 Expression and Predict Immune Signatures in Melanoma Patients.
Aoude LG, Wong BZY, Bonazzi VF, Brosda S, Walters SB, Koufariotis LT, Naeini MM, Pearson JV, Oey H, Patel K, Bradford JJ, Bloxham CJ, Atkinson V, Law P, Strutton G, Bayley G, Yang S, Smithers BM, Waddell N, Miles K, Barbour AP. Aoude LG, et al. Mol Cancer Res. 2021 Jun;19(6):950-956. doi: 10.1158/1541-7786.MCR-20-1038. Epub 2021 Apr 2. Mol Cancer Res. 2021. PMID: 33811161
ctDNA as a biomarker of progression in oesophageal adenocarcinoma.
Bonazzi VF, Aoude LG, Brosda S, Lonie JM, Patel K, Bradford JJ, Koufariotis LT, Wood S, Smithers BM, Waddell N, Barbour AP. Bonazzi VF, et al. Among authors: aoude lg. ESMO Open. 2022 Jun;7(3):100452. doi: 10.1016/j.esmoop.2022.100452. Epub 2022 Mar 23. ESMO Open. 2022. PMID: 35798469 Free PMC article.
Multi-omic features of oesophageal adenocarcinoma in patients treated with preoperative neoadjuvant therapy.
M Naeini M, Newell F, Aoude LG, Bonazzi VF, Patel K, Lampe G, Koufariotis LT, Lakis V, Addala V, Kondrashova O, Johnston RL, Sharma S, Brosda S, Holmes O, Leonard C, Wood S, Xu Q, Thomas J, Walpole E, Tao Mai G, Ackland SP, Martin J, Burge M, Finch R, Karapetis CS, Shannon J, Nott L, Bohmer R, Wilson K, Barnes E, Zalcberg JR, Mark Smithers B, Simes J, Price T, Gebski V, Nones K, Watson DI, Pearson JV, Barbour AP, Waddell N. M Naeini M, et al. Among authors: aoude lg. Nat Commun. 2023 May 31;14(1):3155. doi: 10.1038/s41467-023-38891-x. Nat Commun. 2023. PMID: 37258531 Free PMC article.
38 results