York JM - Search Results

1

APOE4 homozygote females are resistant to the beneficial effects of 17β-estradiol on memory and CA1 dendritic spine density in the EFAD mouse model of Alzheimer's disease.

Taxier LR, Philippi SM, Fleischer AW, York JM, LaDu MJ, Frick KM. Taxier LR, et al. Among authors: york jm. Neurobiol Aging. 2022 Oct;118:13-24. doi: 10.1016/j.neurobiolaging.2022.06.005. Epub 2022 Jun 23. Neurobiol Aging. 2022. PMID: 35843109 Free PMC article.

2

APOE4 Induces Site-Specific Tau Phosphorylation Through Calpain-CDK5 Signaling Pathway in EFAD-Tg Mice.

Zhou M, Huang T, Collins N, Zhang J, Shen H, Dai X, Xiao N, Wu X, Wei Z, York J, Lin L, Zhu Y, LaDu MJ, Chen X. Zhou M, et al. Curr Alzheimer Res. 2016;13(9):1048-55. doi: 10.2174/1567205013666160415154550. Curr Alzheimer Res. 2016. PMID: 27087442

3

The role of APOE in transgenic mouse models of AD.

Balu D, Karstens AJ, Loukenas E, Maldonado Weng J, York JM, Valencia-Olvera AC, LaDu MJ. Balu D, et al. Among authors: york jm. Neurosci Lett. 2019 Aug 10;707:134285. doi: 10.1016/j.neulet.2019.134285. Epub 2019 May 28. Neurosci Lett. 2019. PMID: 31150730 Free PMC article. Review.

4

Synergistic effects of APOE and sex on the gut microbiome of young EFAD transgenic mice.

Maldonado Weng J, Parikh I, Naqib A, York J, Green SJ, Estus S, LaDu MJ. Maldonado Weng J, et al. Mol Neurodegener. 2019 Dec 20;14(1):47. doi: 10.1186/s13024-019-0352-2. Mol Neurodegener. 2019. PMID: 31861986 Free PMC article.

5

The detrimental effects of APOE4 on risk for Alzheimer's disease may result from altered dendritic spine density, synaptic proteins, and estrogen receptor alpha.

Taxier LR, Philippi SM, York JM, LaDu MJ, Frick KM. Taxier LR, et al. Among authors: york jm. Neurobiol Aging. 2022 Apr;112:74-86. doi: 10.1016/j.neurobiolaging.2021.12.006. Epub 2021 Dec 24. Neurobiol Aging. 2022. PMID: 35051676 Free PMC article.

6

APOE4 genotype or ovarian hormone loss influence open field exploration in an EFAD mouse model of Alzheimer's disease.

Taxier LR, Philippi SM, York JM, LaDu MJ, Frick KM. Taxier LR, et al. Among authors: york jm. Horm Behav. 2022 Apr;140:105124. doi: 10.1016/j.yhbeh.2022.105124. Epub 2022 Jan 29. Horm Behav. 2022. PMID: 35101701 Free PMC article.

7

Inhibition of ACAT as a Therapeutic Target for Alzheimer's Disease Is Independent of ApoE4 Lipidation.

Valencia-Olvera AC, Balu D, Faulk N, Amiridis A, Wang Y, Pham C, Avila-Munoz E, York JM, Thatcher GRJ, LaDu MJ. Valencia-Olvera AC, et al. Among authors: york jm. Neurotherapeutics. 2023 Jul;20(4):1120-1137. doi: 10.1007/s13311-023-01375-3. Epub 2023 May 8. Neurotherapeutics. 2023. PMID: 37157042 Free PMC article.

8

A small-molecule TLR4 antagonist reduced neuroinflammation in female E4FAD mice.

Balu D, Valencia-Olvera AC, Nguyen A, Patnam M, York J, Peri F, Neumann F, LaDu MJ, Tai LM. Balu D, et al. Alzheimers Res Ther. 2023 Oct 19;15(1):181. doi: 10.1186/s13195-023-01330-6. Alzheimers Res Ther. 2023. PMID: 37858252 Free PMC article.

9

APOE genotype and sex modulate Alzheimer's disease pathology in aged EFAD transgenic mice.

Balu D, Valencia-Olvera AC, Islam Z, Mielczarek C, Hansen A, Perez Ramos TM, York J, LaDu MJ, Tai LM. Balu D, et al. Front Aging Neurosci. 2023 Oct 31;15:1279343. doi: 10.3389/fnagi.2023.1279343. eCollection 2023. Front Aging Neurosci. 2023. PMID: 38020764 Free PMC article.

10

A novel apoE-mimetic increases brain apoE levels, reduces Aβ pathology and improves memory when treated before onset of pathology in male mice that express APOE3.

Valencia-Olvera AC, Balu D, Bellur S, McNally T, Saleh Y, Pham D, Ghura S, York J, Johansson JO, LaDu MJ, Tai L. Valencia-Olvera AC, et al. Alzheimers Res Ther. 2023 Dec 15;15(1):216. doi: 10.1186/s13195-023-01353-z. Alzheimers Res Ther. 2023. PMID: 38102668 Free PMC article.

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