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Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets.
Dempster JM, Pacini C, Pantel S, Behan FM, Green T, Krill-Burger J, Beaver CM, Younger ST, Zhivich V, Najgebauer H, Allen F, Gonçalves E, Shepherd R, Doench JG, Yusa K, Vazquez F, Parts L, Boehm JS, Golub TR, Hahn WC, Root DE, Garnett MJ, Tsherniak A, Iorio F. Dempster JM, et al. Among authors: iorio f. Nat Commun. 2019 Dec 20;10(1):5817. doi: 10.1038/s41467-019-13805-y. Nat Commun. 2019. PMID: 31862961 Free PMC article.
CELLector: Genomics-Guided Selection of Cancer In Vitro Models.
Najgebauer H, Yang M, Francies HE, Pacini C, Stronach EA, Garnett MJ, Saez-Rodriguez J, Iorio F. Najgebauer H, et al. Among authors: iorio f. Cell Syst. 2020 May 20;10(5):424-432.e6. doi: 10.1016/j.cels.2020.04.007. Cell Syst. 2020. PMID: 32437684 Free article.
Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens.
Gonçalves E, Segura-Cabrera A, Pacini C, Picco G, Behan FM, Jaaks P, Coker EA, van der Meer D, Barthorpe A, Lightfoot H, Mironenko T, Beck A, Richardson L, Yang W, Lleshi E, Hall J, Tolley C, Hall C, Mali I, Thomas F, Morris J, Leach AR, Lynch JT, Sidders B, Crafter C, Iorio F, Fawell S, Garnett MJ. Gonçalves E, et al. Among authors: iorio f. Mol Syst Biol. 2020 Jul;16(7):e9405. doi: 10.15252/msb.20199405. Mol Syst Biol. 2020. PMID: 32627965 Free PMC article.
Cancer research needs a better map.
Boehm JS, Garnett MJ, Adams DJ, Francies HE, Golub TR, Hahn WC, Iorio F, McFarland JM, Parts L, Vazquez F. Boehm JS, et al. Among authors: iorio f. Nature. 2021 Jan;589(7843):514-516. doi: 10.1038/d41586-021-00182-0. Nature. 2021. PMID: 33500573 No abstract available.
Integrated cross-study datasets of genetic dependencies in cancer.
Pacini C, Dempster JM, Boyle I, Gonçalves E, Najgebauer H, Karakoc E, van der Meer D, Barthorpe A, Lightfoot H, Jaaks P, McFarland JM, Garnett MJ, Tsherniak A, Iorio F. Pacini C, et al. Among authors: iorio f. Nat Commun. 2021 Mar 12;12(1):1661. doi: 10.1038/s41467-021-21898-7. Nat Commun. 2021. PMID: 33712601 Free PMC article.
Highlights from the 1st European cancer dependency map symposium and workshop.
Trastulla L, Savino A, Beltrao P, Ciriano IC, Fenici P, Garnett MJ, Guerini I, Bigas NL, Mattaj I, Petsalaki E, Riva L, Tape CJ, Leeuwen JV, Sharma S, Vazquez F, Iorio F. Trastulla L, et al. Among authors: iorio f. FEBS Lett. 2023 Aug;597(15):1921-1927. doi: 10.1002/1873-3468.14699. Epub 2023 Jul 24. FEBS Lett. 2023. PMID: 37487655 Free article.
191 results