Pouysségur J - Search Results

1

'Warburg effect' controls tumor growth, bacterial, viral infections and immunity - Genetic deconstruction and therapeutic perspectives.

Pouysségur J, Marchiq I, Parks SK, Durivault J, Ždralević M, Vucetic M. Pouysségur J, et al. Semin Cancer Biol. 2022 Nov;86(Pt 2):334-346. doi: 10.1016/j.semcancer.2022.07.004. Epub 2022 Jul 9. Semin Cancer Biol. 2022. PMID: 35820598 Free article. Review.

2

pH control mechanisms of tumor survival and growth.

Parks SK, Chiche J, Pouyssegur J. Parks SK, et al. Among authors: pouyssegur j. J Cell Physiol. 2011 Feb;226(2):299-308. doi: 10.1002/jcp.22400. J Cell Physiol. 2011. PMID: 20857482 Review.

3

The HIF-1-inducible lysyl oxidase activates HIF-1 via the Akt pathway in a positive regulation loop and synergizes with HIF-1 in promoting tumor cell growth.

Pez F, Dayan F, Durivault J, Kaniewski B, Aimond G, Le Provost GS, Deux B, Clézardin P, Sommer P, Pouysségur J, Reynaud C. Pez F, et al. Among authors: pouyssegur j. Cancer Res. 2011 Mar 1;71(5):1647-57. doi: 10.1158/0008-5472.CAN-10-1516. Epub 2011 Jan 14. Cancer Res. 2011. PMID: 21239473

4

CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors.

Le Floch R, Chiche J, Marchiq I, Naiken T, Ilc K, Murray CM, Critchlow SE, Roux D, Simon MP, Pouysségur J. Le Floch R, et al. Among authors: pouyssegur j. Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16663-8. doi: 10.1073/pnas.1106123108. Epub 2011 Sep 19. Proc Natl Acad Sci U S A. 2011. PMID: 21930917 Free PMC article.

5

The asparaginyl hydroxylase factor-inhibiting HIF is essential for tumor growth through suppression of the p53-p21 axis.

Pelletier J, Dayan F, Durivault J, Ilc K, Pécou E, Pouysségur J, Mazure NM. Pelletier J, et al. Among authors: pouyssegur j. Oncogene. 2012 Jun 14;31(24):2989-3001. doi: 10.1038/onc.2011.471. Epub 2011 Oct 17. Oncogene. 2012. PMID: 22002313

6

Knock-down of hypoxia-induced carbonic anhydrases IX and XII radiosensitizes tumor cells by increasing intracellular acidosis.

Doyen J, Parks SK, Marcié S, Pouysségur J, Chiche J. Doyen J, et al. Among authors: pouyssegur j. Front Oncol. 2013 Jan 7;2:199. doi: 10.3389/fonc.2012.00199. eCollection 2012. Front Oncol. 2013. PMID: 23316475 Free PMC article.

7

Hypoxia promotes tumor cell survival in acidic conditions by preserving ATP levels.

Parks SK, Mazure NM, Counillon L, Pouysségur J. Parks SK, et al. Among authors: pouyssegur j. J Cell Physiol. 2013 Sep;228(9):1854-62. doi: 10.1002/jcp.24346. J Cell Physiol. 2013. PMID: 23459996

8

MiR-210 promotes a hypoxic phenotype and increases radioresistance in human lung cancer cell lines.

Grosso S, Doyen J, Parks SK, Bertero T, Paye A, Cardinaud B, Gounon P, Lacas-Gervais S, Noël A, Pouysségur J, Barbry P, Mazure NM, Mari B. Grosso S, et al. Among authors: pouyssegur j. Cell Death Dis. 2013 Mar 14;4(3):e544. doi: 10.1038/cddis.2013.71. Cell Death Dis. 2013. PMID: 23492775 Free PMC article.

9

Disrupting proton dynamics and energy metabolism for cancer therapy.

Parks SK, Chiche J, Pouysségur J. Parks SK, et al. Among authors: pouyssegur j. Nat Rev Cancer. 2013 Sep;13(9):611-23. doi: 10.1038/nrc3579. Nat Rev Cancer. 2013. PMID: 23969692 Review.

10

Gene disruption using zinc finger nuclease technology.

Granja S, Marchiq I, Baltazar F, Pouysségur J. Granja S, et al. Among authors: pouyssegur j. Methods Mol Biol. 2014;1165:253-60. doi: 10.1007/978-1-4939-0856-1_17. Methods Mol Biol. 2014. PMID: 24839030

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