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Page 1
Characterization of Renal Injury and Inflammation in an Experimental Model of Intravascular Hemolysis.
Merle NS, Grunenwald A, Figueres ML, Chauvet S, Daugan M, Knockaert S, Robe-Rybkine T, Noe R, May O, Frimat M, Brinkman N, Gentinetta T, Miescher S, Houillier P, Legros V, Gonnet F, Blanc-Brude OP, Rabant M, Daniel R, Dimitrov JD, Roumenina LT. Merle NS, et al. Among authors: grunenwald a. Front Immunol. 2018 Mar 1;9:179. doi: 10.3389/fimmu.2018.00179. eCollection 2018. Front Immunol. 2018. PMID: 29545789 Free PMC article.
Intravascular hemolysis activates complement via cell-free heme and heme-loaded microvesicles.
Merle NS, Grunenwald A, Rajaratnam H, Gnemmi V, Frimat M, Figueres ML, Knockaert S, Bouzekri S, Charue D, Noe R, Robe-Rybkine T, Le-Hoang M, Brinkman N, Gentinetta T, Edler M, Petrillo S, Tolosano E, Miescher S, Le Jeune S, Houillier P, Chauvet S, Rabant M, Dimitrov JD, Fremeaux-Bacchi V, Blanc-Brude OP, Roumenina LT. Merle NS, et al. Among authors: grunenwald a. JCI Insight. 2018 Jun 21;3(12):e96910. doi: 10.1172/jci.insight.96910. eCollection 2018 Jun 21. JCI Insight. 2018. PMID: 29925688 Free PMC article.
Circulating FH Protects Kidneys From Tubular Injury During Systemic Hemolysis.
Merle NS, Leon J, Poillerat V, Grunenwald A, Boudhabhay I, Knockaert S, Robe-Rybkine T, Torset C, Pickering MC, Chauvet S, Fremeaux-Bacchi V, Roumenina LT. Merle NS, et al. Among authors: grunenwald a. Front Immunol. 2020 Aug 7;11:1772. doi: 10.3389/fimmu.2020.01772. eCollection 2020. Front Immunol. 2020. PMID: 32849636 Free PMC article.
Complement activation is a crucial driver of acute kidney injury in rhabdomyolysis.
Boudhabhay I, Poillerat V, Grunenwald A, Torset C, Leon J, Daugan MV, Lucibello F, El Karoui K, Ydee A, Chauvet S, Girardie P, Sacks S, Farrar CA, Garred P, Berthaud R, Le Quintrec M, Rabant M, de Lonlay P, Rambaud C, Gnemmi V, Fremeaux-Bacchi V, Frimat M, Roumenina LT. Boudhabhay I, et al. Among authors: grunenwald a. Kidney Int. 2021 Mar;99(3):581-597. doi: 10.1016/j.kint.2020.09.033. Epub 2020 Nov 1. Kidney Int. 2021. PMID: 33137339 Free article.
A role for complement blockade in kidney transplantation.
Karpman D, Bekassy Z, Grunenwald A, Roumenina LT. Karpman D, et al. Among authors: grunenwald a. Cell Mol Immunol. 2022 Jul;19(7):755-757. doi: 10.1038/s41423-022-00854-5. Epub 2022 Mar 24. Cell Mol Immunol. 2022. PMID: 35332298 Free PMC article. No abstract available.
C3-dependent effector functions of complement.
Zarantonello A, Revel M, Grunenwald A, Roumenina LT. Zarantonello A, et al. Among authors: grunenwald a. Immunol Rev. 2023 Jan;313(1):120-138. doi: 10.1111/imr.13147. Epub 2022 Oct 22. Immunol Rev. 2023. PMID: 36271889 Free PMC article. Review.
Complement involvement in sickle cell disease.
Meuleman MS, Roumenina LT, Grunenwald A. Meuleman MS, et al. Among authors: grunenwald a. Presse Med. 2023 Dec;52(4):104205. doi: 10.1016/j.lpm.2023.104205. Epub 2023 Nov 14. Presse Med. 2023. PMID: 37972851 Review.
Heme Drives Susceptibility of Glomerular Endothelium to Complement Overactivation Due to Inefficient Upregulation of Heme Oxygenase-1.
May O, Merle NS, Grunenwald A, Gnemmi V, Leon J, Payet C, Robe-Rybkine T, Paule R, Delguste F, Satchell SC, Mathieson PW, Hazzan M, Boulanger E, Dimitrov JD, Fremeaux-Bacchi V, Frimat M, Roumenina LT. May O, et al. Among authors: grunenwald a. Front Immunol. 2018 Dec 20;9:3008. doi: 10.3389/fimmu.2018.03008. eCollection 2018. Front Immunol. 2018. PMID: 30619356 Free PMC article.
29 results