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LIGHT (TNFSF14) Costimulation Enhances Myeloid Cell Activation and Antitumor Immunity in the Setting of PD-1/PD-L1 and TIGIT Checkpoint Blockade.
Yoo KJ, Johannes K, González LE, Patel A, Shuptrine CW, Opheim Z, Lenz K, Campbell K, Nguyen TA, Miriyala J, Smith C, McGuire A, Tsai YH, Rangwala F, de Silva S, Schreiber TH, Fromm G. Yoo KJ, et al. Among authors: fromm g. J Immunol. 2022 Aug 1;209(3):510-525. doi: 10.4049/jimmunol.2101175. Epub 2022 Jul 11. J Immunol. 2022. PMID: 35817517 Free PMC article.
Cutting Edge: Bispecific γδ T Cell Engager Containing Heterodimeric BTN2A1 and BTN3A1 Promotes Targeted Activation of Vγ9Vδ2+ T Cells in the Presence of Costimulation by CD28 or NKG2D.
Lai AY, Patel A, Brewer F, Evans K, Johannes K, González LE, Yoo KJ, Fromm G, Wilson K, Schreiber TH, de Silva S. Lai AY, et al. Among authors: fromm g. J Immunol. 2022 Oct 15;209(8):1475-1480. doi: 10.4049/jimmunol.2200185. Epub 2022 Sep 12. J Immunol. 2022. PMID: 36096643 Free PMC article.
Reversal of indoleamine 2,3-dioxygenase-mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme.
Triplett TA, Garrison KC, Marshall N, Donkor M, Blazeck J, Lamb C, Qerqez A, Dekker JD, Tanno Y, Lu WC, Karamitros CS, Ford K, Tan B, Zhang XM, McGovern K, Coma S, Kumada Y, Yamany MS, Sentandreu E, Fromm G, Tiziani S, Schreiber TH, Manfredi M, Ehrlich LIR, Stone E, Georgiou G. Triplett TA, et al. Among authors: fromm g. Nat Biotechnol. 2018 Sep;36(8):758-764. doi: 10.1038/nbt.4180. Epub 2018 Jul 16. Nat Biotechnol. 2018. PMID: 30010674 Free PMC article.
201 results