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De novo prion aggregates trigger autophagy in skeletal muscle.
Joshi-Barr S, Bett C, Chiang WC, Trejo M, Goebel HH, Sikorska B, Liberski P, Raeber A, Lin JH, Masliah E, Sigurdson CJ. Joshi-Barr S, et al. Among authors: sigurdson cj. J Virol. 2014 Feb;88(4):2071-82. doi: 10.1128/JVI.02279-13. Epub 2013 Dec 4. J Virol. 2014. PMID: 24307586 Free PMC article.
Multiple Mechanisms of Unfolded Protein Response-Induced Cell Death.
Hiramatsu N, Chiang WC, Kurt TD, Sigurdson CJ, Lin JH. Hiramatsu N, et al. Among authors: sigurdson cj. Am J Pathol. 2015 Jul;185(7):1800-8. doi: 10.1016/j.ajpath.2015.03.009. Epub 2015 May 5. Am J Pathol. 2015. PMID: 25956028 Free PMC article. Review.
Generation of novel neuroinvasive prions following intravenous challenge.
Aguilar-Calvo P, Bett C, Sevillano AM, Kurt TD, Lawrence J, Soldau K, Hammarström P, Nilsson KPR, Sigurdson CJ. Aguilar-Calvo P, et al. Among authors: sigurdson cj. Brain Pathol. 2018 Nov;28(6):999-1011. doi: 10.1111/bpa.12598. Epub 2018 Jul 5. Brain Pathol. 2018. PMID: 29505163 Free PMC article.
Shortening heparan sulfate chains prolongs survival and reduces parenchymal plaques in prion disease caused by mobile, ADAM10-cleaved prions.
Aguilar-Calvo P, Sevillano AM, Bapat J, Soldau K, Sandoval DR, Altmeppen HC, Linsenmeier L, Pizzo DP, Geschwind MD, Sanchez H, Appleby BS, Cohen ML, Safar JG, Edland SD, Glatzel M, Nilsson KPR, Esko JD, Sigurdson CJ. Aguilar-Calvo P, et al. Among authors: sigurdson cj. Acta Neuropathol. 2020 Mar;139(3):527-546. doi: 10.1007/s00401-019-02085-x. Epub 2019 Oct 31. Acta Neuropathol. 2020. PMID: 31673874 Free PMC article.
Prion protein glycans reduce intracerebral fibril formation and spongiosis in prion disease.
Sevillano AM, Aguilar-Calvo P, Kurt TD, Lawrence JA, Soldau K, Nam TH, Schumann T, Pizzo DP, Nyström S, Choudhury B, Altmeppen H, Esko JD, Glatzel M, Nilsson KPR, Sigurdson CJ. Sevillano AM, et al. Among authors: sigurdson cj. J Clin Invest. 2020 Mar 2;130(3):1350-1362. doi: 10.1172/JCI131564. J Clin Invest. 2020. PMID: 31985492 Free PMC article.
81 results