Fabian MR - Search Results

1

P-bodies directly regulate MARF1-mediated mRNA decay in human cells.

Brothers WR, Fakim H, Kajjo S, Fabian MR. Brothers WR, et al. Among authors: fabian mr. Nucleic Acids Res. 2022 Jul 22;50(13):7623-7636. doi: 10.1093/nar/gkac557. Nucleic Acids Res. 2022. PMID: 35801873 Free PMC article.

2

Regulation of mRNA translation and stability by microRNAs.

Fabian MR, Sonenberg N, Filipowicz W. Fabian MR, et al. Annu Rev Biochem. 2010;79:351-79. doi: 10.1146/annurev-biochem-060308-103103. Annu Rev Biochem. 2010. PMID: 20533884 Review.

3

The eIF4E-Binding Protein 4E-T Is a Component of the mRNA Decay Machinery that Bridges the 5' and 3' Termini of Target mRNAs.

Nishimura T, Padamsi Z, Fakim H, Milette S, Dunham WH, Gingras AC, Fabian MR. Nishimura T, et al. Among authors: fabian mr. Cell Rep. 2015 Jun 9;11(9):1425-36. doi: 10.1016/j.celrep.2015.04.065. Epub 2015 May 28. Cell Rep. 2015. PMID: 26027925 Free article.

4

Molecular architecture of LSM14 interactions involved in the assembly of mRNA silencing complexes.

Brandmann T, Fakim H, Padamsi Z, Youn JY, Gingras AC, Fabian MR, Jinek M. Brandmann T, et al. Among authors: fabian mr. EMBO J. 2018 Apr 3;37(7):e97869. doi: 10.15252/embj.201797869. Epub 2018 Mar 6. EMBO J. 2018. PMID: 29510985 Free PMC article.

5

Human MARF1 is an endoribonuclease that interacts with the DCP1:2 decapping complex and degrades target mRNAs.

Nishimura T, Fakim H, Brandmann T, Youn JY, Gingras AC, Jinek M, Fabian MR. Nishimura T, et al. Among authors: fabian mr. Nucleic Acids Res. 2018 Dec 14;46(22):12008-12021. doi: 10.1093/nar/gky1011. Nucleic Acids Res. 2018. PMID: 30364987 Free PMC article.

6

Communication Is Key: 5'-3' Interactions that Regulate mRNA Translation and Turnover.

Fakim H, Fabian MR. Fakim H, et al. Among authors: fabian mr. Adv Exp Med Biol. 2019;1203:149-164. doi: 10.1007/978-3-030-31434-7_6. Adv Exp Med Biol. 2019. PMID: 31811634

7

A non-canonical role for the EDC4 decapping factor in regulating MARF1-mediated mRNA decay.

Brothers WR, Hebert S, Kleinman CL, Fabian MR. Brothers WR, et al. Among authors: fabian mr. Elife. 2020 Jun 8;9:e54995. doi: 10.7554/eLife.54995. Elife. 2020. PMID: 32510323 Free PMC article.

8

A Cell-Free System for Investigating Human MARF1 Endonuclease Activity.

Fakim H, Fabian MR. Fakim H, et al. Among authors: fabian mr. Methods Mol Biol. 2021;2209:333-345. doi: 10.1007/978-1-0716-0935-4_21. Methods Mol Biol. 2021. PMID: 33201479

9

PABP prevents the untimely decay of select mRNA populations in human cells.

Kajjo S, Sharma S, Chen S, Brothers WR, Cott M, Hasaj B, Jovanovic P, Larsson O, Fabian MR. Kajjo S, et al. Among authors: fabian mr. EMBO J. 2022 Mar 15;41(6):e108650. doi: 10.15252/embj.2021108650. Epub 2022 Feb 14. EMBO J. 2022. PMID: 35156721 Free PMC article.

10

The EDC4-XRN1 interaction controls P-body dynamics to link mRNA decapping with decay.

Brothers WR, Ali F, Kajjo S, Fabian MR. Brothers WR, et al. Among authors: fabian mr. EMBO J. 2023 Nov 2;42(21):e113933. doi: 10.15252/embj.2023113933. Epub 2023 Aug 25. EMBO J. 2023. PMID: 37621215 Free PMC article.

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