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Physiology-based IVIVE predictions of tramadol from in vitro metabolism data.
T'jollyn H, Snoeys J, Colin P, Van Bocxlaer J, Annaert P, Cuyckens F, Vermeulen A, Van Peer A, Allegaert K, Mannens G, Boussery K. T'jollyn H, et al. Among authors: annaert p. Pharm Res. 2015 Jan;32(1):260-74. doi: 10.1007/s11095-014-1460-x. Epub 2014 Jul 22. Pharm Res. 2015. PMID: 25048637
Physiologically Based Pharmacokinetic Predictions of Tramadol Exposure Throughout Pediatric Life: an Analysis of the Different Clearance Contributors with Emphasis on CYP2D6 Maturation.
T'jollyn H, Snoeys J, Vermeulen A, Michelet R, Cuyckens F, Mannens G, Van Peer A, Annaert P, Allegaert K, Van Bocxlaer J, Boussery K. T'jollyn H, et al. Among authors: annaert p. AAPS J. 2015 Nov;17(6):1376-87. doi: 10.1208/s12248-015-9803-z. Epub 2015 Jul 25. AAPS J. 2015. PMID: 26209290 Free PMC article.
Strategies for Determining Correct Cytochrome P450 Contributions in Hepatic Clearance Predictions: In Vitro-In Vivo Extrapolation as Modelling Approach and Tramadol as Proof-of Concept Compound.
T'jollyn H, Snoeys J, Van Bocxlaer J, De Bock L, Annaert P, Van Peer A, Allegaert K, Mannens G, Vermeulen A, Boussery K. T'jollyn H, et al. Among authors: annaert p. Eur J Drug Metab Pharmacokinet. 2017 Jun;42(3):537-543. doi: 10.1007/s13318-016-0355-0. Eur J Drug Metab Pharmacokinet. 2017. PMID: 27317395
219 results