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A time-resolved, multi-symbol molecular recorder via sequential genome editing.
Choi J, Chen W, Minkina A, Chardon FM, Suiter CC, Regalado SG, Domcke S, Hamazaki N, Lee C, Martin B, Daza RM, Shendure J. Choi J, et al. Among authors: regalado sg. Nature. 2022 Aug;608(7921):98-107. doi: 10.1038/s41586-022-04922-8. Epub 2022 Jul 6. Nature. 2022. PMID: 35794474 Free PMC article.
Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle.
Sinha M, Jang YC, Oh J, Khong D, Wu EY, Manohar R, Miller C, Regalado SG, Loffredo FS, Pancoast JR, Hirshman MF, Lebowitz J, Shadrach JL, Cerletti M, Kim MJ, Serwold T, Goodyear LJ, Rosner B, Lee RT, Wagers AJ. Sinha M, et al. Among authors: regalado sg. Science. 2014 May 9;344(6184):649-52. doi: 10.1126/science.1251152. Epub 2014 May 5. Science. 2014. PMID: 24797481 Free PMC article.
A Single-Cell Atlas of In Vivo Mammalian Chromatin Accessibility.
Cusanovich DA, Hill AJ, Aghamirzaie D, Daza RM, Pliner HA, Berletch JB, Filippova GN, Huang X, Christiansen L, DeWitt WS, Lee C, Regalado SG, Read DF, Steemers FJ, Disteche CM, Trapnell C, Shendure J. Cusanovich DA, et al. Among authors: regalado sg. Cell. 2018 Aug 23;174(5):1309-1324.e18. doi: 10.1016/j.cell.2018.06.052. Epub 2018 Aug 2. Cell. 2018. PMID: 30078704 Free PMC article.
Human intestinal tissue with adult stem cell properties derived from pluripotent stem cells.
Forster R, Chiba K, Schaeffer L, Regalado SG, Lai CS, Gao Q, Kiani S, Farin HF, Clevers H, Cost GJ, Chan A, Rebar EJ, Urnov FD, Gregory PD, Pachter L, Jaenisch R, Hockemeyer D. Forster R, et al. Among authors: regalado sg. Stem Cell Reports. 2014 Jun 3;2(6):838-52. doi: 10.1016/j.stemcr.2014.05.001. eCollection 2014 Jun 3. Stem Cell Reports. 2014. PMID: 24936470 Free PMC article.
Multiplex, single-cell CRISPRa screening for cell type specific regulatory elements.
Chardon FM, McDiarmid TA, Page NF, Daza RM, Martin BK, Domcke S, Regalado SG, Lalanne JB, Calderon D, Li X, Starita LM, Sanders SJ, Ahituv N, Shendure J. Chardon FM, et al. Among authors: regalado sg. Nat Commun. 2024 Sep 18;15(1):8209. doi: 10.1038/s41467-024-52490-4. Nat Commun. 2024. PMID: 39294132 Free PMC article.
16 results