Qi YK - Search Results

1

The hybrid oncolytic peptide NTP-385 potently inhibits adherent cancer cells by targeting the nucleus.

Yin H, Chen XT, Chi QN, Ma YN, Fu XY, Du SS, Qi YK, Wang KW. Yin H, et al. Among authors: qi yk. Acta Pharmacol Sin. 2023 Jan;44(1):201-210. doi: 10.1038/s41401-022-00939-x. Epub 2022 Jul 6. Acta Pharmacol Sin. 2023. PMID: 35794372 Free PMC article.

2

DIC/Oxyma-based accelerated synthesis and oxidative folding studies of centipede toxin RhTx.

Chen XT, Wang JY, Ma YN, Dong LY, Jia SX, Yin H, Fu XY, Du SS, Qi YK, Wang K. Chen XT, et al. Among authors: qi yk. J Pept Sci. 2022 Mar;28(3):e3368. doi: 10.1002/psc.3368. Epub 2021 Sep 12. J Pept Sci. 2022. PMID: 34514664

3

Binding ability of methylene blue with heparin dependent on its sulfate level rather than its sulfation location or basic saccharide structure.

Jia SX, Chi QN, Zhang Y, Liu T, Kou X, Wang F, Qi YK, Du SS, Xing XH. Jia SX, et al. Among authors: qi yk. Glycoconj J. 2021 Oct;38(5):551-560. doi: 10.1007/s10719-021-10010-2. Epub 2021 Sep 13. Glycoconj J. 2021. PMID: 34515908

4

Discovery, synthesis, and optimization of teixobactin, a novel antibiotic without detectable bacterial resistance.

Qi YK, Tang X, Wei NN, Pang CJ, Du SS, Wang K. Qi YK, et al. J Pept Sci. 2022 Nov;28(11):e3428. doi: 10.1002/psc.3428. Epub 2022 Jun 13. J Pept Sci. 2022. PMID: 35610021 Review.

5

Efficient synthesis and anticancer evaluation of spider toxin peptide LVTX-8-based analogues with enhanced stability.

Chi QN, Jia SX, Yin H, Wang LE, Fu XY, Ma YN, Sun MP, Qi YK, Li Z, Du SS. Chi QN, et al. Among authors: qi yk. Bioorg Chem. 2023 May;134:106451. doi: 10.1016/j.bioorg.2023.106451. Epub 2023 Mar 2. Bioorg Chem. 2023. PMID: 36907048

6

Three Rounds of Stability-Guided Optimization and Systematical Evaluation of Oncolytic Peptide LTX-315.

Fu XY, Yin H, Chen XT, Yao JF, Ma YN, Song M, Xu H, Yu QY, Du SS, Qi YK, Wang KW. Fu XY, et al. Among authors: qi yk. J Med Chem. 2024 Mar 14;67(5):3885-3908. doi: 10.1021/acs.jmedchem.3c02232. Epub 2024 Jan 26. J Med Chem. 2024. PMID: 38278140

7

Synthesis and structural optimization of oncolytic peptide LTX-315.

Song M, Liu Q, Yao JF, Wang YT, Ma YN, Xu H, Yu QY, Li Z, Du SS, Qi YK. Song M, et al. Among authors: qi yk. Bioorg Med Chem. 2024 Jun 1;107:117760. doi: 10.1016/j.bmc.2024.117760. Epub 2024 May 15. Bioorg Med Chem. 2024. PMID: 38762978

8

Design and synthesis of TH19P01-Camptothecin based hybrid peptides inducing effective anticancer responses on sortilin positive cancer cells.

Li YJ, Fang CB, Wang SS, Chen XQ, Li Y, Liu Q, Qi YK, Du SS. Li YJ, et al. Among authors: qi yk. Bioorg Med Chem. 2024 Sep 1;111:117869. doi: 10.1016/j.bmc.2024.117869. Epub 2024 Aug 3. Bioorg Med Chem. 2024. PMID: 39126834

9

Structure-guided peptide engineering of a positive allosteric modulator targeting the outer pore of TRPV1 for long-lasting analgesia.

Zhang H, Lin JJ, Xie YK, Song XZ, Sun JY, Zhang BL, Qi YK, Xu ZZ, Yang F. Zhang H, et al. Among authors: qi yk. Nat Commun. 2023 Jan 3;14(1):4. doi: 10.1038/s41467-022-34817-1. Nat Commun. 2023. PMID: 36596769 Free PMC article.

10

Rational design and synthesis of Oreoch-2 analogues as efficient broad-spectrum antimicrobial peptides.

Zhang N, Gu X, Song D, Zhang P, Zhang N, Chen W, Ji S, Qi Y, Ma S. Zhang N, et al. Bioorg Chem. 2022 Feb;119:105583. doi: 10.1016/j.bioorg.2021.105583. Epub 2021 Dec 24. Bioorg Chem. 2022. PMID: 34971943

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