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Page 1
A cyclic peptide toolkit reveals mechanistic principles of peptidylarginine deiminase IV regulation.
Bertran MT, Walmsley R, Cummings T, Aramburu IV, Benton DJ, Mora Molina R, Assalaarachchi J, Chasampalioti M, Swanton T, Joshi D, Federico S, Okkenhaug H, Yu L, Oxley D, Walker S, Papayannopoulos V, Suga H, Christophorou MA, Walport LJ. Bertran MT, et al. Among authors: aramburu iv. Nat Commun. 2024 Nov 11;15(1):9746. doi: 10.1038/s41467-024-53554-1. Nat Commun. 2024. PMID: 39528459 Free PMC article.
Anti-inflammatory therapy with nebulized dornase alfa for severe COVID-19 pneumonia: a randomized unblinded trial.
Porter JC, Inshaw J, Solis VJ, Denneny E, Evans R, Temkin MI, De Vasconcelos N, Aramburu IV, Hoving D, Basire D, Crissell T, Guinto J, Webb A, Esmail H, Johnston V, Last A, Rampling T, Lippert L, Helbig ET, Kurth F, Williams B, Flynn A, Lukey PT, Birault V, Papayannopoulos V. Porter JC, et al. Among authors: aramburu iv. Elife. 2024 Jul 16;12:RP87030. doi: 10.7554/eLife.87030. Elife. 2024. PMID: 39009040 Free PMC article. Clinical Trial.
Loss of TET2 in human hematopoietic stem cells alters the development and function of neutrophils.
Huerga Encabo H, Aramburu IV, Garcia-Albornoz M, Piganeau M, Wood H, Song A, Ferrelli A, Sharma A, Minutti CM, Domart MC, Papazoglou D, Gurashi K, Llorian Sopena M, Goldstone R, Fallesen T, Wang Q, Ariza-McNaughton L, Wiseman DH, Batta K, Gupta R, Papayannopoulos V, Bonnet D. Huerga Encabo H, et al. Among authors: aramburu iv. Cell Stem Cell. 2023 Jun 1;30(6):781-799.e9. doi: 10.1016/j.stem.2023.05.004. Cell Stem Cell. 2023. PMID: 37267914 Free article.
Functional proteomic profiling links deficient DNA clearance with increased mortality in individuals with severe COVID-19 pneumonia.
Aramburu IV, Hoving D, Vernardis SI, Tin MCF, Ioannou M, Temkin MI, De Vasconcelos NM, Demichev V, Helbig ET, Lippert L, Stahl K, White M, Radbruch H, Ihlow J, Horst D, Chiesa ST, Deanfield JE, David S, Bode C, Kurth F, Ralser M, Papayannopoulos V. Aramburu IV, et al. Immunity. 2022 Dec 13;55(12):2436-2453.e5. doi: 10.1016/j.immuni.2022.11.007. Epub 2022 Nov 17. Immunity. 2022. PMID: 36462503 Free PMC article.
Microbe capture by splenic macrophages triggers sepsis via T cell-death-dependent neutrophil lifespan shortening.
Ioannou M, Hoving D, Aramburu IV, Temkin MI, De Vasconcelos NM, Tsourouktsoglou TD, Wang Q, Boeing S, Goldstone R, Vernardis S, Demichev V, Ralser M, David S, Stahl K, Bode C, Papayannopoulos V. Ioannou M, et al. Among authors: aramburu iv. Nat Commun. 2022 Aug 9;13(1):4658. doi: 10.1038/s41467-022-32320-1. Nat Commun. 2022. PMID: 35945238 Free PMC article.
Motor Fluctuations Development Is Associated with Non-Motor Symptoms Burden Progression in Parkinson's Disease Patients: A 2-Year Follow-Up Study.
Santos-García D, de Deus Fonticoba T, Bartolomé CC, Painceiras MJF, Castro ES, Canfield H, Miró CM, Jesús S, Aguilar M, Pastor P, Planellas L, Cosgaya M, Caldentey JG, Caballol N, Legarda I, Hernández-Vara J, Cabo I, Manzanares LL, Aramburu IG, Rivera MAÁ, Mayordomo VG, Nogueira V, Puente V, García-Soto JD, Borrué C, Vila BS, Sauco MÁ, Vela L, Escalante S, Cubo E, Padilla FC, Castrillo JCM, Alonso PS, Losada MGA, Ariztegui NL, Gastón I, Kulisevsky J, Estrada MB, Seijo M, Martínez JR, Valero C, Kurtis M, de Fábregues O, Ardura JG, Redondo RA, Ordás C, Díaz LML, McAfee D, Martinez-Martin P, Mir P, Coppadis Study Group. Santos-García D, et al. Among authors: aramburu ig. Diagnostics (Basel). 2022 May 5;12(5):1147. doi: 10.3390/diagnostics12051147. Diagnostics (Basel). 2022. PMID: 35626303 Free PMC article.
Increased homocysteine levels correlate with cortical structural damage in Parkinson's disease.
Sampedro F, Martínez-Horta S, Horta-Barba A, Grothe MJ, Labrador-Espinosa MA, Jesús S, Adarmes-Gómez A, Carrillo F, Puig-Davi A, Lora FR, Barberá MA, Pastor P, Arroyo SE, Vila BS, Foraster AC, Martínez JR, Padilla FC, Morlans MP, Aramburu IG, Ceberio JI, Vara JH, de Fábregues-Boixar O, de Deus Fonticoba T, Ávila A, Martínez-Castrillo JC, Bejr-Kasem H, Campolongo A, Pascual-Sedano B; COPPADIS Study Group; Martínez-Martín P, Santos-García D, Mir P, Kulisevsky J. Sampedro F, et al. Among authors: aramburu ig. J Neurol Sci. 2022 Mar 15;434:120148. doi: 10.1016/j.jns.2022.120148. Epub 2022 Jan 12. J Neurol Sci. 2022. PMID: 35085959
Neutrophil extracellular traps: from physiology to pathology.
Hidalgo A, Libby P, Soehnlein O, Aramburu IV, Papayannopoulos V, Silvestre-Roig C. Hidalgo A, et al. Among authors: aramburu iv. Cardiovasc Res. 2022 Oct 21;118(13):2737-2753. doi: 10.1093/cvr/cvab329. Cardiovasc Res. 2022. PMID: 34648022 Free PMC article. Review.
39 results