Izgu EC - Search Results

1

Introducing a New Bond-Forming Activity in an Archaeal DNA Polymerase by Structure-Guided Enzyme Redesign.

Aggarwal T, Hansen WA, Hong J, Ganguly A, York DM, Khare SD, Izgu EC. Aggarwal T, et al. Among authors: izgu ec. ACS Chem Biol. 2022 Jul 15;17(7):1924-1936. doi: 10.1021/acschembio.2c00373. Epub 2022 Jul 1. ACS Chem Biol. 2022. PMID: 35776893 Free PMC article.

2

MicroRNA detection in biologically relevant media using a split aptamer platform.

Wang L, Hast K, Aggarwal T, Baci M, Hong J, Izgu EC. Wang L, et al. Among authors: izgu ec. Bioorg Med Chem. 2022 Sep 1;69:116909. doi: 10.1016/j.bmc.2022.116909. Epub 2022 Jun 27. Bioorg Med Chem. 2022. PMID: 35779513 Free PMC article.

3

Bioorthogonal Functionalization of Material Surfaces with Bioactive Molecules.

Hast K, Stone MRL, Jia Z, Baci M, Aggarwal T, Izgu EC. Hast K, et al. Among authors: izgu ec. ACS Appl Mater Interfaces. 2023 Feb 1;15(4):4996-5009. doi: 10.1021/acsami.2c20942. Epub 2023 Jan 17. ACS Appl Mater Interfaces. 2023. PMID: 36649474 Free PMC article.

4

A Small-Molecule Approach to Bypass In Vitro Selection of New Aptamers: Designer Pre-Ligands Turn Baby Spinach into Sensors for Reactive Inorganic Targets.

Aggarwal T, Wang L, Gutierrez B, Guven H, Erguven H, Izgu EC. Aggarwal T, et al. Among authors: izgu ec. bioRxiv [Preprint]. 2023 Dec 13:2023.07.29.551132. doi: 10.1101/2023.07.29.551132. bioRxiv. 2023. PMID: 38168427 Free PMC article. Preprint.

5

Benzylic Trifluoromethyl Accelerates 1,6-Elimination Toward Rapid Probe Activation.

Wang L, Sivakumar A, Zhang R, Cho S, Kim Y, Aggarwal T, Wang L, Izgu EC. Wang L, et al. Among authors: izgu ec. bioRxiv [Preprint]. 2024 May 31:2024.05.30.596105. doi: 10.1101/2024.05.30.596105. bioRxiv. 2024. PMID: 38854154 Free PMC article. Preprint.

6

Downstream Oligonucleotides Strongly Enhance the Affinity of GMP to RNA Primer-Template Complexes.

Tam CP, Fahrenbach AC, Björkbom A, Prywes N, Izgu EC, Szostak JW. Tam CP, et al. Among authors: izgu ec. J Am Chem Soc. 2017 Jan 18;139(2):571-574. doi: 10.1021/jacs.6b09760. Epub 2017 Jan 5. J Am Chem Soc. 2017. PMID: 28055190 Free PMC article.

7

DNA polymerase activity on synthetic N3'→P5' phosphoramidate DNA templates.

Lelyveld VS, O'Flaherty DK, Zhou L, Izgu EC, Szostak JW. Lelyveld VS, et al. Among authors: izgu ec. Nucleic Acids Res. 2019 Sep 26;47(17):8941-8949. doi: 10.1093/nar/gkz707. Nucleic Acids Res. 2019. PMID: 31428779 Free PMC article.

8

Catecholamine-Copper Redox as a Basis for Site-Specific Single-Step Functionalization of Material Surfaces.

Jia Z, Hast K, Izgu EC. Jia Z, et al. Among authors: izgu ec. ACS Appl Mater Interfaces. 2021 Jan 27;13(3):4711-4722. doi: 10.1021/acsami.0c19396. Epub 2021 Jan 14. ACS Appl Mater Interfaces. 2021. PMID: 33444000 Free PMC article.

9

Uncovering the thermodynamics of monomer binding for RNA replication.

Izgu EC, Fahrenbach AC, Zhang N, Li L, Zhang W, Larsen AT, Blain JC, Szostak JW. Izgu EC, et al. J Am Chem Soc. 2015 May 20;137(19):6373-82. doi: 10.1021/jacs.5b02707. Epub 2015 May 7. J Am Chem Soc. 2015. PMID: 25901790 Free PMC article.

10

Synthesis of activated 3'-amino-3'-deoxy-2-thio-thymidine, a superior substrate for the nonenzymatic copying of nucleic acid templates.

Izgu EC, Oh SS, Szostak JW. Izgu EC, et al. Chem Commun (Camb). 2016 Mar 4;52(18):3684-6. doi: 10.1039/c5cc10317g. Chem Commun (Camb). 2016. PMID: 26857159 Free article.

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