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Page 1
Calmodulin kinase II is required for fight or flight sinoatrial node physiology.
Wu Y, Gao Z, Chen B, Koval OM, Singh MV, Guan X, Hund TJ, Kutschke W, Sarma S, Grumbach IM, Wehrens XH, Mohler PJ, Song LS, Anderson ME. Wu Y, et al. Among authors: grumbach im. Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5972-7. doi: 10.1073/pnas.0806422106. Epub 2009 Mar 10. Proc Natl Acad Sci U S A. 2009. PMID: 19276108 Free PMC article.
CaV1.2 beta-subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations.
Koval OM, Guan X, Wu Y, Joiner ML, Gao Z, Chen B, Grumbach IM, Luczak ED, Colbran RJ, Song LS, Hund TJ, Mohler PJ, Anderson ME. Koval OM, et al. Among authors: grumbach im. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):4996-5000. doi: 10.1073/pnas.0913760107. Epub 2010 Mar 1. Proc Natl Acad Sci U S A. 2010. PMID: 20194790 Free PMC article.
Oxidation of CaMKII determines the cardiotoxic effects of aldosterone.
He BJ, Joiner ML, Singh MV, Luczak ED, Swaminathan PD, Koval OM, Kutschke W, Allamargot C, Yang J, Guan X, Zimmerman K, Grumbach IM, Weiss RM, Spitz DR, Sigmund CD, Blankesteijn WM, Heymans S, Mohler PJ, Anderson ME. He BJ, et al. Among authors: grumbach im. Nat Med. 2011 Nov 13;17(12):1610-8. doi: 10.1038/nm.2506. Nat Med. 2011. PMID: 22081025 Free PMC article.
CaMKII is essential for the proasthmatic effects of oxidation.
Sanders PN, Koval OM, Jaffer OA, Prasad AM, Businga TR, Scott JA, Hayden PJ, Luczak ED, Dickey DD, Allamargot C, Olivier AK, Meyerholz DK, Robison AJ, Winder DG, Blackwell TS, Dworski R, Sammut D, Wagner BA, Buettner GR, Pope RM, Miller FJ Jr, Dibbern ME, Haitchi HM, Mohler PJ, Howarth PH, Zabner J, Kline JN, Grumbach IM, Anderson ME. Sanders PN, et al. Among authors: grumbach im. Sci Transl Med. 2013 Jul 24;5(195):195ra97. doi: 10.1126/scitranslmed.3006135. Sci Transl Med. 2013. PMID: 23884469 Free PMC article.
Calcium/calmodulin-dependent kinase II inhibition in smooth muscle reduces angiotensin II-induced hypertension by controlling aortic remodeling and baroreceptor function.
Prasad AM, Morgan DA, Nuno DW, Ketsawatsomkron P, Bair TB, Venema AN, Dibbern ME, Kutschke WJ, Weiss RM, Lamping KG, Chapleau MW, Sigmund CD, Rahmouni K, Grumbach IM. Prasad AM, et al. Among authors: grumbach im. J Am Heart Assoc. 2015 Jun 15;4(6):e001949. doi: 10.1161/JAHA.115.001949. J Am Heart Assoc. 2015. PMID: 26077587 Free PMC article.
CaMKII inhibition in type II pneumocytes protects from bleomycin-induced pulmonary fibrosis by preventing Ca2+-dependent apoptosis.
Winters CJ, Koval O, Murthy S, Allamargot C, Sebag SC, Paschke JD, Jaffer OA, Carter AB, Grumbach IM. Winters CJ, et al. Among authors: grumbach im. Am J Physiol Lung Cell Mol Physiol. 2016 Jan 1;310(1):L86-94. doi: 10.1152/ajplung.00132.2015. Epub 2015 Nov 6. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 26545899 Free PMC article.
Role of CaMKII in Ang-II-dependent small artery remodeling.
Prasad AM, Ketsawatsomkron P, Nuno DW, Koval OM, Dibbern ME, Venema AN, Sigmund CD, Lamping KG, Grumbach IM. Prasad AM, et al. Among authors: grumbach im. Vascul Pharmacol. 2016 Dec;87:172-179. doi: 10.1016/j.vph.2016.09.007. Epub 2016 Sep 20. Vascul Pharmacol. 2016. PMID: 27658984 Free PMC article.
87 results