Mercola M - Search Results

1

Reengineering Ponatinib to Minimize Cardiovascular Toxicity.

Hnatiuk AP, Bruyneel AAN, Tailor D, Pandrala M, Dheeraj A, Li W, Serrano R, Feyen DAM, Vu MM, Amatya P, Gupta S, Nakauchi Y, Morgado I, Wiebking V, Liao R, Porteus MH, Majeti R, Malhotra SV, Mercola M. Hnatiuk AP, et al. Among authors: mercola m. Cancer Res. 2022 Aug 3;82(15):2777-2791. doi: 10.1158/0008-5472.CAN-21-3652. Cancer Res. 2022. PMID: 35763671 Free PMC article.

2

High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells.

Sharma A, Burridge PW, McKeithan WL, Serrano R, Shukla P, Sayed N, Churko JM, Kitani T, Wu H, Holmström A, Matsa E, Zhang Y, Kumar A, Fan AC, Del Álamo JC, Wu SM, Moslehi JJ, Mercola M, Wu JC. Sharma A, et al. Among authors: mercola m. Sci Transl Med. 2017 Feb 15;9(377):eaaf2584. doi: 10.1126/scitranslmed.aaf2584. Sci Transl Med. 2017. PMID: 28202772 Free PMC article.

3

An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes.

McKeithan WL, Savchenko A, Yu MS, Cerignoli F, Bruyneel AAN, Price JH, Colas AR, Miller EW, Cashman JR, Mercola M. McKeithan WL, et al. Among authors: mercola m. Front Physiol. 2017 Oct 11;8:766. doi: 10.3389/fphys.2017.00766. eCollection 2017. Front Physiol. 2017. PMID: 29075196 Free PMC article.

4

Using iPSC Models to Probe Regulation of Cardiac Ion Channel Function.

Bruyneel AAN, McKeithan WL, Feyen DAM, Mercola M. Bruyneel AAN, et al. Among authors: mercola m. Curr Cardiol Rep. 2018 May 25;20(7):57. doi: 10.1007/s11886-018-1000-0. Curr Cardiol Rep. 2018. PMID: 29802473 Review.

5

A Novel Inhibitor Targets Both Wnt Signaling and ATM/p53 in Colorectal Cancer.

Cheng J, Dwyer M, Okolotowicz KJ, Mercola M, Cashman JR. Cheng J, et al. Among authors: mercola m. Cancer Res. 2018 Sep 1;78(17):5072-5083. doi: 10.1158/0008-5472.CAN-17-2642. Epub 2018 Jul 21. Cancer Res. 2018. PMID: 30032112

6

Will iPSC-cardiomyocytes revolutionize the discovery of drugs for heart disease?

Bruyneel AA, McKeithan WL, Feyen DA, Mercola M. Bruyneel AA, et al. Among authors: mercola m. Curr Opin Pharmacol. 2018 Oct;42:55-61. doi: 10.1016/j.coph.2018.07.003. Epub 2018 Aug 3. Curr Opin Pharmacol. 2018. PMID: 30081259 Free PMC article. Review.

7

Use of human induced pluripotent stem cell-derived cardiomyocytes to assess drug cardiotoxicity.

Sharma A, McKeithan WL, Serrano R, Kitani T, Burridge PW, Del Álamo JC, Mercola M, Wu JC. Sharma A, et al. Among authors: mercola m. Nat Protoc. 2018 Dec;13(12):3018-3041. doi: 10.1038/s41596-018-0076-8. Nat Protoc. 2018. PMID: 30413796 Free PMC article.

8

Stars in the Night Sky: iPSC-Cardiomyocytes Return the Patient Context to Drug Screening.

Hnatiuk A, Mercola M. Hnatiuk A, et al. Among authors: mercola m. Cell Stem Cell. 2019 Apr 4;24(4):506-507. doi: 10.1016/j.stem.2019.03.013. Cell Stem Cell. 2019. PMID: 30951657 Free article.

9

Disruption of NOTCH signaling by a small molecule inhibitor of the transcription factor RBPJ.

Hurtado C, Safarova A, Smith M, Chung R, Bruyneel AAN, Gomez-Galeno J, Oswald F, Larson CJ, Cashman JR, Ruiz-Lozano P, Janiak P, Suzuki T, Mercola M. Hurtado C, et al. Among authors: mercola m. Sci Rep. 2019 Jul 25;9(1):10811. doi: 10.1038/s41598-019-46948-5. Sci Rep. 2019. PMID: 31346210 Free PMC article.

10

AlleleProfileR: A versatile tool to identify and profile sequence variants in edited genomes.

Bruyneel AAN, Colas AR, Karakikes I, Mercola M. Bruyneel AAN, et al. Among authors: mercola m. PLoS One. 2019 Dec 26;14(12):e0226694. doi: 10.1371/journal.pone.0226694. eCollection 2019. PLoS One. 2019. PMID: 31877162 Free PMC article.

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