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Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease.
Assante G, Chandrasekaran S, Ng S, Tourna A, Chung CH, Isse KA, Banks JL, Soffientini U, Filippi C, Dhawan A, Liu M, Rozen SG, Hoare M, Campbell P, Ballard JWO, Turner N, Morris MJ, Chokshi S, Youngson NA. Assante G, et al. Among authors: rozen sg. Genome Med. 2022 Jun 23;14(1):67. doi: 10.1186/s13073-022-01071-5. Genome Med. 2022. PMID: 35739588 Free PMC article.
Genome-scale mutational signatures of aflatoxin in cells, mice, and human tumors.
Huang MN, Yu W, Teoh WW, Ardin M, Jusakul A, Ng AWT, Boot A, Abedi-Ardekani B, Villar S, Myint SS, Othman R, Poon SL, Heguy A, Olivier M, Hollstein M, Tan P, Teh BT, Sabapathy K, Zavadil J, Rozen SG. Huang MN, et al. Among authors: rozen sg. Genome Res. 2017 Sep;27(9):1475-1486. doi: 10.1101/gr.220038.116. Epub 2017 Jul 24. Genome Res. 2017. PMID: 28739859 Free PMC article.
Mutation signatures implicate aristolochic acid in bladder cancer development.
Poon SL, Huang MN, Choo Y, McPherson JR, Yu W, Heng HL, Gan A, Myint SS, Siew EY, Ler LD, Ng LG, Weng WH, Chuang CK, Yuen JS, Pang ST, Tan P, Teh BT, Rozen SG. Poon SL, et al. Among authors: rozen sg. Genome Med. 2015 Apr 28;7(1):38. doi: 10.1186/s13073-015-0161-3. eCollection 2015. Genome Med. 2015. PMID: 26015808 Free PMC article.
Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance.
Vettore AL, Ramnarayanan K, Poore G, Lim K, Ong CK, Huang KK, Leong HS, Chong FT, Lim TK, Lim WK, Cutcutache I, Mcpherson JR, Suzuki Y, Zhang S, Skanthakumar T, Wang W, Tan DS, Cho BC, Teh BT, Rozen S, Tan P, Iyer NG. Vettore AL, et al. Genome Med. 2015 Sep 23;7(1):98. doi: 10.1186/s13073-015-0219-2. Genome Med. 2015. PMID: 26395002 Free PMC article.
Experimental and pan-cancer genome analyses reveal widespread contribution of acrylamide exposure to carcinogenesis in humans.
Zhivagui M, Ng AWT, Ardin M, Churchwell MI, Pandey M, Renard C, Villar S, Cahais V, Robitaille A, Bouaoun L, Heguy A, Guyton KZ, Stampfer MR, McKay J, Hollstein M, Olivier M, Rozen SG, Beland FA, Korenjak M, Zavadil J. Zhivagui M, et al. Among authors: rozen sg. Genome Res. 2019 Apr;29(4):521-531. doi: 10.1101/gr.242453.118. Epub 2019 Mar 7. Genome Res. 2019. PMID: 30846532 Free PMC article.
170 results