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Molecular correlates of clinical response and resistance to atezolizumab in combination with bevacizumab in advanced hepatocellular carcinoma.
Zhu AX, Abbas AR, de Galarreta MR, Guan Y, Lu S, Koeppen H, Zhang W, Hsu CH, He AR, Ryoo BY, Yau T, Kaseb AO, Burgoyne AM, Dayyani F, Spahn J, Verret W, Finn RS, Toh HC, Lujambio A, Wang Y. Zhu AX, et al. Among authors: de galarreta mr. Nat Med. 2022 Aug;28(8):1599-1611. doi: 10.1038/s41591-022-01868-2. Epub 2022 Jun 23. Nat Med. 2022. PMID: 35739268
Unfolded protein response induced by Brefeldin A increases collagen type I levels in hepatic stellate cells through an IRE1α, p38 MAPK and Smad-dependent pathway.
de Galarreta MR, Navarro A, Ansorena E, Garzón AG, Mòdol T, López-Zabalza MJ, Martínez-Irujo JJ, Iraburu MJ. de Galarreta MR, et al. Biochim Biophys Acta. 2016 Aug;1863(8):2115-23. doi: 10.1016/j.bbamcr.2016.05.002. Epub 2016 May 4. Biochim Biophys Acta. 2016. PMID: 27155082 Free article.