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Page 1
Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy.
Chaffin M, Papangeli I, Simonson B, Akkad AD, Hill MC, Arduini A, Fleming SJ, Melanson M, Hayat S, Kost-Alimova M, Atwa O, Ye J, Bedi KC Jr, Nahrendorf M, Kaushik VK, Stegmann CM, Margulies KB, Tucker NR, Ellinor PT. Chaffin M, et al. Among authors: stegmann cm. Nature. 2022 Aug;608(7921):174-180. doi: 10.1038/s41586-022-04817-8. Epub 2022 Jun 22. Nature. 2022. PMID: 35732739
Transcriptional and Cellular Diversity of the Human Heart.
Tucker NR, Chaffin M, Fleming SJ, Hall AW, Parsons VA, Bedi KC Jr, Akkad AD, Herndon CN, Arduini A, Papangeli I, Roselli C, Aguet F, Choi SH, Ardlie KG, Babadi M, Margulies KB, Stegmann CM, Ellinor PT. Tucker NR, et al. Among authors: stegmann cm. Circulation. 2020 Aug 4;142(5):466-482. doi: 10.1161/CIRCULATIONAHA.119.045401. Epub 2020 May 14. Circulation. 2020. PMID: 32403949 Free PMC article.
Deep learning enables genetic analysis of the human thoracic aorta.
Pirruccello JP, Chaffin MD, Chou EL, Fleming SJ, Lin H, Nekoui M, Khurshid S, Friedman SF, Bick AG, Arduini A, Weng LC, Choi SH, Akkad AD, Batra P, Tucker NR, Hall AW, Roselli C, Benjamin EJ, Vellarikkal SK, Gupta RM, Stegmann CM, Juric D, Stone JR, Vasan RS, Ho JE, Hoffmann U, Lubitz SA, Philippakis AA, Lindsay ME, Ellinor PT. Pirruccello JP, et al. Among authors: stegmann cm. Nat Genet. 2022 Jan;54(1):40-51. doi: 10.1038/s41588-021-00962-4. Epub 2021 Nov 26. Nat Genet. 2022. PMID: 34837083 Free PMC article.
Myocyte-Specific Upregulation of ACE2 in Cardiovascular Disease: Implications for SARS-CoV-2-Mediated Myocarditis.
Tucker NR, Chaffin M, Bedi KC Jr, Papangeli I, Akkad AD, Arduini A, Hayat S, Eraslan G, Muus C, Bhattacharyya RP, Stegmann CM; Human Cell Atlas Lung Biological Network; Margulies KB, Ellinor PT; Human Cell Atlas Lung Biological Network Consortium Members. Tucker NR, et al. Among authors: stegmann cm. Circulation. 2020 Aug 18;142(7):708-710. doi: 10.1161/CIRCULATIONAHA.120.047911. Epub 2020 Jun 22. Circulation. 2020. PMID: 32795091 Free PMC article.
Myocyte Specific Upregulation of ACE2 in Cardiovascular Disease: Implications for SARS-CoV-2 mediated myocarditis.
Tucker NR, Chaffin M, Bedi KC, Papangeli I, Akkad AD, Arduini A, Hayat S, Eraslan G, Muus C, Bhattacharyya R, Stegmann CM, Margulies KB, Ellinor PT. Tucker NR, et al. Among authors: stegmann cm. medRxiv [Preprint]. 2020 Apr 14:2020.04.09.20059204. doi: 10.1101/2020.04.09.20059204. medRxiv. 2020. Update in: Circulation. 2020 Aug 18;142(7):708-710. doi: 10.1161/CIRCULATIONAHA.120.047911 PMID: 32511660 Free PMC article. Updated. Preprint.
Transcriptional profile of the rat cardiovascular system at single-cell resolution.
Arduini A, Fleming SJ, Xiao L, Hall AW, Akkad AD, Chaffin MD, Bendinelli KJ, Tucker NR, Papangeli I, Mantineo H, Flores-Bringas P, Babadi M, Stegmann CM, García-Cardeña G, Lindsay ME, Klattenhoff C, Ellinor PT. Arduini A, et al. Among authors: stegmann cm. Cell Rep. 2024 Dec 21;44(1):115091. doi: 10.1016/j.celrep.2024.115091. Online ahead of print. Cell Rep. 2024. PMID: 39709602 Free article.
Transcriptional profile of the rat cardiovascular system at single cell resolution.
Arduini A, Fleming SJ, Xiao L, Hall AW, Akkad AD, Chaffin M, Bendinelli KJ, Tucker NR, Papangeli I, Mantineo H, Babadi M, Stegmann CM, García-Cardeña G, Lindsay ME, Klattenhoff C, Ellinor PT. Arduini A, et al. Among authors: stegmann cm. bioRxiv [Preprint]. 2023 Nov 16:2023.11.14.567085. doi: 10.1101/2023.11.14.567085. bioRxiv. 2023. Update in: Cell Rep. 2024 Dec 21;44(1):115091. doi: 10.1016/j.celrep.2024.115091 PMID: 38014050 Free PMC article. Updated. Preprint.
Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction.
Hillig RC, Sautier B, Schroeder J, Moosmayer D, Hilpmann A, Stegmann CM, Werbeck ND, Briem H, Boemer U, Weiske J, Badock V, Mastouri J, Petersen K, Siemeister G, Kahmann JD, Wegener D, Böhnke N, Eis K, Graham K, Wortmann L, von Nussbaum F, Bader B. Hillig RC, et al. Among authors: stegmann cm. Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2551-2560. doi: 10.1073/pnas.1812963116. Epub 2019 Jan 25. Proc Natl Acad Sci U S A. 2019. PMID: 30683722 Free PMC article.
Binding kinetics in drug discovery - A current perspective.
Georgi V, Andres D, Fernandez-Montalvan AE, Stegmann CM, Becker A, Mueller-Fahrnow A. Georgi V, et al. Among authors: stegmann cm. Front Biosci (Landmark Ed). 2017 Jan 1;22(1):21-47. doi: 10.2741/4470. Front Biosci (Landmark Ed). 2017. PMID: 27814600 Free article. Review.
19 results