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Type 1 diabetes in diverse ancestries and the use of genetic risk scores.
Redondo MJ, Gignoux CR, Dabelea D, Hagopian WA, Onengut-Gumuscu S, Oram RA, Rich SS. Redondo MJ, et al. Among authors: oram ra. Lancet Diabetes Endocrinol. 2022 Aug;10(8):597-608. doi: 10.1016/S2213-8587(22)00159-0. Epub 2022 Jun 17. Lancet Diabetes Endocrinol. 2022. PMID: 35724677 Free PMC article. Review.
Systematic Population Screening, Using Biomarkers and Genetic Testing, Identifies 2.5% of the U.K. Pediatric Diabetes Population With Monogenic Diabetes.
Shepherd M, Shields B, Hammersley S, Hudson M, McDonald TJ, Colclough K, Oram RA, Knight B, Hyde C, Cox J, Mallam K, Moudiotis C, Smith R, Fraser B, Robertson S, Greene S, Ellard S, Pearson ER, Hattersley AT; UNITED Team. Shepherd M, et al. Among authors: oram ra. Diabetes Care. 2016 Nov;39(11):1879-1888. doi: 10.2337/dc16-0645. Epub 2016 Jun 6. Diabetes Care. 2016. PMID: 27271189 Free PMC article.
Genetic risk scores in adult-onset type 1 diabetes - Authors' reply.
Thomas NJ, Jones SE, Weedon MN, Shields BM, Hattersley AT, Oram RA. Thomas NJ, et al. Among authors: oram ra. Lancet Diabetes Endocrinol. 2018 Mar;6(3):169. doi: 10.1016/S2213-8587(18)30046-9. Lancet Diabetes Endocrinol. 2018. PMID: 29475496 No abstract available.
Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children.
Bonifacio E, Beyerlein A, Hippich M, Winkler C, Vehik K, Weedon MN, Laimighofer M, Hattersley AT, Krumsiek J, Frohnert BI, Steck AK, Hagopian WA, Krischer JP, Lernmark Å, Rewers MJ, She JX, Toppari J, Akolkar B, Oram RA, Rich SS, Ziegler AG; TEDDY Study Group. Bonifacio E, et al. Among authors: oram ra. PLoS Med. 2018 Apr 3;15(4):e1002548. doi: 10.1371/journal.pmed.1002548. eCollection 2018 Apr. PLoS Med. 2018. PMID: 29614081 Free PMC article.
Clinical and research uses of genetic risk scores in type 1 diabetes.
Sharp SA, Weedon MN, Hagopian WA, Oram RA. Sharp SA, et al. Among authors: oram ra. Curr Opin Genet Dev. 2018 Jun;50:96-102. doi: 10.1016/j.gde.2018.03.009. Epub 2018 Apr 24. Curr Opin Genet Dev. 2018. PMID: 29702327 Free PMC article. Review.
135 results