Hoffmann A - Search Results

1

Quantifying information of intracellular signaling: progress with machine learning.

Tang Y, Hoffmann A. Tang Y, et al. Among authors: hoffmann a. Rep Prog Phys. 2022 Jul 12;85(8):10.1088/1361-6633/ac7a4a. doi: 10.1088/1361-6633/ac7a4a. Rep Prog Phys. 2022. PMID: 35724636 Free PMC article. Review.

2

Systems biology. Accurate information transmission through dynamic biochemical signaling networks.

Selimkhanov J, Taylor B, Yao J, Pilko A, Albeck J, Hoffmann A, Tsimring L, Wollman R. Selimkhanov J, et al. Among authors: hoffmann a. Science. 2014 Dec 12;346(6215):1370-3. doi: 10.1126/science.1254933. Science. 2014. PMID: 25504722 Free PMC article.

3

An incoherent feedforward loop interprets NFκB/RelA dynamics to determine TNF-induced necroptosis decisions.

Oliver Metzig M, Tang Y, Mitchell S, Taylor B, Foreman R, Wollman R, Hoffmann A. Oliver Metzig M, et al. Among authors: hoffmann a. Mol Syst Biol. 2020 Dec;16(12):e9677. doi: 10.15252/msb.20209677. Mol Syst Biol. 2020. PMID: 33314666 Free PMC article.

4

Quantifying information accumulation encoded in the dynamics of biochemical signaling.

Tang Y, Adelaja A, Ye FX, Deeds E, Wollman R, Hoffmann A. Tang Y, et al. Among authors: hoffmann a. Nat Commun. 2021 Feb 24;12(1):1272. doi: 10.1038/s41467-021-21562-0. Nat Commun. 2021. PMID: 33627672 Free PMC article.

5

Six distinct NFκB signaling codons convey discrete information to distinguish stimuli and enable appropriate macrophage responses.

Adelaja A, Taylor B, Sheu KM, Liu Y, Luecke S, Hoffmann A. Adelaja A, et al. Among authors: hoffmann a. Immunity. 2021 May 11;54(5):916-930.e7. doi: 10.1016/j.immuni.2021.04.011. Immunity. 2021. PMID: 33979588 Free PMC article.

6

NF-κB signaling.

O'Dea E, Hoffmann A. O'Dea E, et al. Among authors: hoffmann a. Wiley Interdiscip Rev Syst Biol Med. 2009 Jul-Aug;1(1):107-115. doi: 10.1002/wsbm.30. Wiley Interdiscip Rev Syst Biol Med. 2009. PMID: 20151024 Free PMC article. Review.

7

The dynamics of signaling as a pharmacological target.

Behar M, Barken D, Werner SL, Hoffmann A. Behar M, et al. Among authors: hoffmann a. Cell. 2013 Oct 10;155(2):448-61. doi: 10.1016/j.cell.2013.09.018. Cell. 2013. PMID: 24120141 Free PMC article.

8

A pathway switch directs BAFF signaling to distinct NFκB transcription factors in maturing and proliferating B cells.

Almaden JV, Tsui R, Liu YC, Birnbaum H, Shokhirev MN, Ngo KA, Davis-Turak JC, Otero D, Basak S, Rickert RC, Hoffmann A. Almaden JV, et al. Among authors: hoffmann a. Cell Rep. 2014 Dec 24;9(6):2098-111. doi: 10.1016/j.celrep.2014.11.024. Epub 2014 Dec 11. Cell Rep. 2014. PMID: 25497099 Free PMC article.

9

Studying NF-κB signaling with mathematical models.

Mitchell S, Tsui R, Hoffmann A. Mitchell S, et al. Among authors: hoffmann a. Methods Mol Biol. 2015;1280:647-61. doi: 10.1007/978-1-4939-2422-6_38. Methods Mol Biol. 2015. PMID: 25736777

10

Distinct single-cell signaling characteristics are conferred by the MyD88 and TRIF pathways during TLR4 activation.

Cheng Z, Taylor B, Ourthiague DR, Hoffmann A. Cheng Z, et al. Among authors: hoffmann a. Sci Signal. 2015 Jul 14;8(385):ra69. doi: 10.1126/scisignal.aaa5208. Sci Signal. 2015. PMID: 26175492 Free PMC article.

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