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Distinct mechanisms of innate and adaptive immune regulation underlie poor oncologic outcomes associated with KRAS-TP53 co-alteration in pancreatic cancer.
Datta J, Bianchi A, De Castro Silva I, Deshpande NU, Cao LL, Mehra S, Singh S, Rafie C, Sun X, Chen X, Dai X, Colaprico A, Sharma P, Dosch AR, Pillai A, Hosein PJ, Nagathihalli NS, Komanduri KV, Wilson JM, Ban Y, Merchant NB. Datta J, et al. Among authors: cao ll. Oncogene. 2022 Jul;41(28):3640-3654. doi: 10.1038/s41388-022-02368-w. Epub 2022 Jun 14. Oncogene. 2022. PMID: 35701533
Multivalent tyrosine kinase inhibition promotes T cell recruitment to immune-desert gastric cancers by restricting epithelial-mesenchymal transition via tumour-intrinsic IFN-γ signalling.
Cao LL, Lu H, Soutto M, Bhat N, Chen Z, Peng D, Gomaa A, Wang JB, Xie JW, Li P, Zheng CH, Nomura S, Datta J, Merchant N, Chen ZB, Villarino A, Zaika A, Huang CM, El-Rifai W. Cao LL, et al. Gut. 2023 Nov;72(11):2038-2050. doi: 10.1136/gutjnl-2022-329134. Epub 2023 Jul 4. Gut. 2023. PMID: 37402563 Free PMC article.
425 results