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Novel Small Molecule Tyrosine Kinase 2 Pseudokinase Ligands Block Cytokine-Induced TYK2-Mediated Signaling Pathways.
Zhou Y, Li X, Shen R, Wang X, Zhang F, Liu S, Li D, Liu J, Li P, Yan Y, Dong P, Zhang Z, Wu H, Zhuang L, Chowdhury R, Miller M, Issa M, Mao Y, Chen H, Feng J, Li J, Bai C, He F, Tao W. Zhou Y, et al. Among authors: wu h. Front Immunol. 2022 May 20;13:884399. doi: 10.3389/fimmu.2022.884399. eCollection 2022. Front Immunol. 2022. PMID: 35693820 Free PMC article.
A Novel CD73 Inhibitor SHR170008 Suppresses Adenosine in Tumor and Enhances Anti-Tumor Activity with PD-1 Blockade in a Mouse Model of Breast Cancer.
Liu S, Li D, Liu J, Wang H, Horecny I, Shen R, Zhang R, Wu H, Hu Q, Zhao P, Zhang F, Yan Y, Feng J, Zhuang L, Li J, Zhang L, Tao W. Liu S, et al. Among authors: wu h. Onco Targets Ther. 2021 Aug 24;14:4561-4574. doi: 10.2147/OTT.S326178. eCollection 2021. Onco Targets Ther. 2021. PMID: 34466002 Free PMC article.
Discovery of spiro amide SHR902275: A potent, selective, and efficacious RAF inhibitor targeting RAS mutant cancers.
Zhao P, Zhuang L, Wang X, Huang S, Wu H, Zhou Y, Yan Y, Zhang F, Shen R, Li J, Liu S, Zhang R, Dong P, Mao Y, Fan Y, He C, Sun J, Zhang L, Hu Q, Wan H, Feng J, Bai C, He F, Tao W. Zhao P, et al. Among authors: wu h. Eur J Med Chem. 2022 Jan 15;228:114040. doi: 10.1016/j.ejmech.2021.114040. Epub 2021 Dec 7. Eur J Med Chem. 2022. PMID: 34906761
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