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Novel Small Molecule Tyrosine Kinase 2 Pseudokinase Ligands Block Cytokine-Induced TYK2-Mediated Signaling Pathways.
Zhou Y, Li X, Shen R, Wang X, Zhang F, Liu S, Li D, Liu J, Li P, Yan Y, Dong P, Zhang Z, Wu H, Zhuang L, Chowdhury R, Miller M, Issa M, Mao Y, Chen H, Feng J, Li J, Bai C, He F, Tao W. Zhou Y, et al. Among authors: li d, li j, li x, li p. Front Immunol. 2022 May 20;13:884399. doi: 10.3389/fimmu.2022.884399. eCollection 2022. Front Immunol. 2022. PMID: 35693820 Free PMC article.
SHR1032, a novel STING agonist, stimulates anti-tumor immunity and directly induces AML apoptosis.
Song C, Liu D, Liu S, Li D, Horecny I, Zhang X, Li P, Chen L, Miller M, Chowdhury R, Issa M, Shen R, Yan Y, Zhang F, Zhang L, Zhang L, Bai C, Feng J, Zhuang L, Zhang R, Li J, Wilkinson H, Liu J, Tao W. Song C, et al. Among authors: li d, li j, li p. Sci Rep. 2022 May 20;12(1):8579. doi: 10.1038/s41598-022-12449-1. Sci Rep. 2022. PMID: 35595822 Free PMC article.
Structure-Based Design and Synthesis of Potent and Selective KRAS G12D Inhibitors.
Cheng H, Li P, Chen P, Irimia A, Bae JH, Brooun A, Fagan P, Lam R, Lin B, Zhang J, Zhan X, Wu X, Xie N, Chiang G, Shoemaker R, Vernier JM. Cheng H, et al. Among authors: li p. ACS Med Chem Lett. 2023 Sep 18;14(10):1351-1357. doi: 10.1021/acsmedchemlett.3c00245. eCollection 2023 Oct 12. ACS Med Chem Lett. 2023. PMID: 37849557 Free PMC article.
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