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The SARS-CoV-2 spike L452R-E484Q variant in the Indian B.1.617 strain showed significant reduction in the neutralization activity of immune sera.
Li G, Zhou Z, Du P, Yu M, Li N, Xiong X, Huang H, Liu Z, Dai Q, Zhu J, Guo C, Wu S, Baptista-Hon DT, Miao M, Ming LW, Wu Y, Zeng F, Zhang CL, Zhang ED, Song H, Liu J, Lau JY, Xiang AP, Zhang K. Li G, et al. Among authors: du p. Precis Clin Med. 2021 Jul 30;4(3):149-154. doi: 10.1093/pcmedi/pbab016. eCollection 2021 Sep. Precis Clin Med. 2021. PMID: 35693215 Free PMC article.
HDL-scavenger receptor B type 1 facilitates SARS-CoV-2 entry.
Wei C, Wan L, Yan Q, Wang X, Zhang J, Yang X, Zhang Y, Fan C, Li D, Deng Y, Sun J, Gong J, Yang X, Wang Y, Wang X, Li J, Yang H, Li H, Zhang Z, Wang R, Du P, Zong Y, Yin F, Zhang W, Wang N, Peng Y, Lin H, Feng J, Qin C, Chen W, Gao Q, Zhang R, Cao Y, Zhong H. Wei C, et al. Among authors: du p. Nat Metab. 2020 Dec;2(12):1391-1400. doi: 10.1038/s42255-020-00324-0. Epub 2020 Nov 26. Nat Metab. 2020. PMID: 33244168
CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells.
Wang K, Chen W, Zhang Z, Deng Y, Lian JQ, Du P, Wei D, Zhang Y, Sun XX, Gong L, Yang X, He L, Zhang L, Yang Z, Geng JJ, Chen R, Zhang H, Wang B, Zhu YM, Nan G, Jiang JL, Li L, Wu J, Lin P, Huang W, Xie L, Zheng ZH, Zhang K, Miao JL, Cui HY, Huang M, Zhang J, Fu L, Yang XM, Zhao Z, Sun S, Gu H, Wang Z, Wang CF, Lu Y, Liu YY, Wang QY, Bian H, Zhu P, Chen ZN. Wang K, et al. Among authors: du p. Signal Transduct Target Ther. 2020 Dec 4;5(1):283. doi: 10.1038/s41392-020-00426-x. Signal Transduct Target Ther. 2020. PMID: 33277466 Free PMC article.
CD147 antibody specifically and effectively inhibits infection and cytokine storm of SARS-CoV-2 and its variants delta, alpha, beta, and gamma.
Geng J, Chen L, Yuan Y, Wang K, Wang Y, Qin C, Wu G, Chen R, Zhang Z, Wei D, Du P, Zhang J, Lin P, Zhang K, Deng Y, Xu K, Liu J, Sun X, Guo T, Yang X, Wu J, Jiang J, Li L, Zhang K, Wang Z, Zhang J, Yan Q, Zhu H, Zheng Z, Miao J, Fu X, Yang F, Chen X, Tang H, Zhang Y, Shi Y, Zhu Y, Pei Z, Huo F, Liang X, Wang Y, Wang Q, Xie W, Li Y, Shi M, Bian H, Zhu P, Chen ZN. Geng J, et al. Among authors: du p. Signal Transduct Target Ther. 2021 Sep 25;6(1):347. doi: 10.1038/s41392-021-00760-8. Signal Transduct Target Ther. 2021. PMID: 34564690 Free PMC article.
Immunological and metabolic characteristics of the Omicron variants infection.
Geng J, Yang X, Wang K, Wang K, Chen R, Chen ZN, Qin C, Wu G, Wang Y, Xu K, Du P, Liu J, Chen S, Zhang T, Sun X, Guo T, Shi Y, Zhang Z, Wei D, Lin P, Wang Q, Yuan J, Qu J, Zou J, Liu Y, Lu H, Zhu P, Bian H, Chen L. Geng J, et al. Among authors: du p. Signal Transduct Target Ther. 2023 Jan 21;8(1):42. doi: 10.1038/s41392-022-01265-8. Signal Transduct Target Ther. 2023. PMID: 36681668 Free PMC article.
2,816 results