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Multistage antiplasmodial activity of hydroxyethylamine compounds, in vitro and in vivo evaluations.
Sharma N, Gupta Y, Bansal M, Singh S, Pathak P, Shahbaaz M, Mathur R, Singh J, Kashif M, Grishina M, Potemkin V, Rajendran V, Poonam, Kempaiah P, Singh AP, Rathi B. Sharma N, et al. Among authors: singh ap, singh j, singh s. RSC Adv. 2020 Sep 25;10(58):35516-35530. doi: 10.1039/d0ra03997g. eCollection 2020 Sep 21. RSC Adv. 2020. PMID: 35686031 Free PMC article.
Antiplasmodial activity of hydroxyethylamine analogs: Synthesis, biological activity and structure activity relationship of plasmepsin inhibitors.
Kumar Singh A, Rajendran V, Singh S, Kumar P, Kumar Y, Singh A, Miller W, Potemkin V, Poonam, Grishina M, Gupta N, Kempaiah P, Durvasula R, Singh BK, Dunn BM, Rathi B. Kumar Singh A, et al. Among authors: singh bk, singh s, singh a. Bioorg Med Chem. 2018 Jul 30;26(13):3837-3844. doi: 10.1016/j.bmc.2018.06.037. Epub 2018 Jun 28. Bioorg Med Chem. 2018. PMID: 29983285
Fast-Acting Small Molecules Targeting Malarial Aspartyl Proteases, Plasmepsins, Inhibit Malaria Infection at Multiple Life Stages.
Singh S, Rajendran V, He J, Singh AK, Achieng AO, Vandana, Pant A, Nasamu AS, Pandit M, Singh J, Quadiri A, Gupta N, Poonam, Ghosh PC, Singh BK, Narayanan L, Kempaiah P, Chandra R, Dunn BM, Pandey KC, Goldberg DE, Singh AP, Rathi B. Singh S, et al. Among authors: singh ap, singh ak, singh j, singh bk. ACS Infect Dis. 2019 Feb 8;5(2):184-198. doi: 10.1021/acsinfecdis.8b00197. Epub 2019 Jan 2. ACS Infect Dis. 2019. PMID: 30554511
The Multistage Antimalarial Compound Calxinin Perturbates P. falciparum Ca2+ Homeostasis by Targeting a Unique Ion Channel.
Gupta Y, Sharma N, Singh S, Romero JG, Rajendran V, Mogire RM, Kashif M, Beach J, Jeske W, Poonam, Ogutu BR, Kanzok SM, Akala HM, Legac J, Rosenthal PJ, Rademacher DJ, Durvasula R, Singh AP, Rathi B, Kempaiah P. Gupta Y, et al. Among authors: singh ap, singh s. Pharmaceutics. 2022 Jun 28;14(7):1371. doi: 10.3390/pharmaceutics14071371. Pharmaceutics. 2022. PMID: 35890267 Free PMC article.
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