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Page 1
Interferon-α-mediated therapeutic resistance in early rheumatoid arthritis implicates epigenetic reprogramming.
Cooles FAH, Tarn J, Lendrem DW, Naamane N, Lin CM, Millar B, Maney NJ, Anderson AE, Thalayasingam N, Diboll J, Bondet V, Duffy D, Barnes MR, Smith GR, Ng S, Watson D, Henkin R, Cope AP, Reynard LN, Pratt AG; RA-MAP Consortium; Isaacs JD. Cooles FAH, et al. Among authors: lendrem dw. Ann Rheum Dis. 2022 Aug 11;81(9):1214-1223. doi: 10.1136/annrheumdis-2022-222370. Ann Rheum Dis. 2022. PMID: 35680389 Free PMC article.
Autonomic symptoms are common and are associated with overall symptom burden and disease activity in primary Sjogren's syndrome.
Newton JL, Frith J, Powell D, Hackett K, Wilton K, Bowman S, Price E, Pease C, Andrews J, Emery P, Hunter J, Gupta M, Vadivelu S, Giles I, Isenberg D, Lanyon P, Jones A, Regan M, Cooper A, Moots R, Sutcliffe N, Bombardieri M, Pitzalis C, McLaren J, Young-Min S, Dasgupta B, Griffiths B, Lendrem D, Mitchell S, Ng WF; UK primary Sjögren's syndrome registry. Newton JL, et al. Ann Rheum Dis. 2012 Dec;71(12):1973-9. doi: 10.1136/annrheumdis-2011-201009. Epub 2012 May 5. Ann Rheum Dis. 2012. PMID: 22562982 Free PMC article.
Health-related utility values of patients with primary Sjögren's syndrome and its predictors.
Lendrem D, Mitchell S, McMeekin P, Bowman S, Price E, Pease CT, Emery P, Andrews J, Lanyon P, Hunter J, Gupta M, Bombardieri M, Sutcliffe N, Pitzalis C, McLaren J, Cooper A, Regan M, Giles I, Isenberg D, Vadivelu S, Coady D, Dasgupta B, McHugh N, Young-Min S, Moots R, Gendi N, Akil M, Griffiths B, Ng WF; UK primary Sjögren's Syndrome Registry. Lendrem D, et al. Ann Rheum Dis. 2014 Jul;73(7):1362-8. doi: 10.1136/annrheumdis-2012-202863. Epub 2013 Jun 12. Ann Rheum Dis. 2014. PMID: 23761688
R&D productivity rides again?
Lendrem D, Senn SJ, Lendrem BC, Isaacs JD. Lendrem D, et al. Pharm Stat. 2015 Jan-Feb;14(1):1-3. doi: 10.1002/pst.1653. Epub 2014 Oct 22. Pharm Stat. 2015. PMID: 25336017 Review.
Why is it hard to terminate failing projects in pharmaceutical R&D?
Peck RW, Lendrem DW, Grant I, Lendrem BC, Isaacs JD. Peck RW, et al. Among authors: lendrem bc, lendrem dw. Nat Rev Drug Discov. 2015 Oct;14(10):663-4. doi: 10.1038/nrd4725. Epub 2015 Aug 21. Nat Rev Drug Discov. 2015. PMID: 26294265
65 results