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Toll-Like Receptor 7 Agonist RG7854 Mediates Therapeutic Efficacy and Seroconversion in Woodchucks With Chronic Hepatitis B.
Wildum S, Korolowicz KE, Suresh M, Steiner G, Dai L, Li B, Yon C, De Vera Mudry MC, Regenass-Lechner F, Huang X, Hong X, Murreddu MG, Kallakury BV, Young JAT, Menne S. Wildum S, et al. Among authors: young jat. Front Immunol. 2022 May 23;13:884113. doi: 10.3389/fimmu.2022.884113. eCollection 2022. Front Immunol. 2022. PMID: 35677037 Free PMC article.
A novel orally available small molecule that inhibits hepatitis B virus expression.
Mueller H, Wildum S, Luangsay S, Walther J, Lopez A, Tropberger P, Ottaviani G, Lu W, Parrott NJ, Zhang JD, Schmucki R, Racek T, Hoflack JC, Kueng E, Point F, Zhou X, Steiner G, Lütgehetmann M, Rapp G, Volz T, Dandri M, Yang S, Young JAT, Javanbakht H. Mueller H, et al. Among authors: young jat. J Hepatol. 2018 Mar;68(3):412-420. doi: 10.1016/j.jhep.2017.10.014. Epub 2017 Oct 25. J Hepatol. 2018. PMID: 29079285 Free article.
Machine-learning based patient classification using Hepatitis B virus full-length genome quasispecies from Asian and European cohorts.
Mueller-Breckenridge AJ, Garcia-Alcalde F, Wildum S, Smits SL, de Man RA, van Campenhout MJH, Brouwer WP, Niu J, Young JAT, Najera I, Zhu L, Wu D, Racek T, Hundie GB, Lin Y, Boucher CA, van de Vijver D, Haagmans BL. Mueller-Breckenridge AJ, et al. Among authors: young jat. Sci Rep. 2019 Dec 11;9(1):18892. doi: 10.1038/s41598-019-55445-8. Sci Rep. 2019. PMID: 31827222 Free PMC article.
Efficacy of an Inhibitor of Hepatitis B Virus Expression in Combination With Entecavir and Interferon-α in Woodchucks Chronically Infected With Woodchuck Hepatitis Virus.
Menne S, Wildum S, Steiner G, Suresh M, Korolowicz K, Balarezo M, Yon C, Murreddu M, Hong X, Kallakury BV, Tucker R, Yang S, Young JAT, Javanbakht H. Menne S, et al. Among authors: young jat. Hepatol Commun. 2020 Apr 22;4(6):916-931. doi: 10.1002/hep4.1502. eCollection 2020 Jun. Hepatol Commun. 2020. PMID: 32490326 Free PMC article.
86 results