Su K - Search Results

1

Tetrahydropyridin-4-ylpicolinoylglycines as novel and orally active prolyl hydroxylase 2 (PHD2) inhibitors for the treatment of renal anemia.

Su K, Li Z, Zhang L, Fang S, Mao M, Sun Z, Zhang X. Su K, et al. Eur J Med Chem. 2022 Aug 5;238:114479. doi: 10.1016/j.ejmech.2022.114479. Epub 2022 May 25. Eur J Med Chem. 2022. PMID: 35675755

2

Photoactivatable Prolyl Hydroxylase 2 Inhibitors for Stabilizing the Hypoxia-Inducible Factor with Light.

Li Z, Su K, Jiang Z, Yu Y, You Q, Zhang X. Li Z, et al. Among authors: su k. J Med Chem. 2019 Aug 22;62(16):7583-7588. doi: 10.1021/acs.jmedchem.9b00688. Epub 2019 Jun 25. J Med Chem. 2019. PMID: 31244107

3

Correction to Photoactivatable Prolyl Hydroxylase 2 Inhibitors for Stabilizing the Hypoxia-Inducible Factor with Light.

Li Z, Su K, Jiang Z, Yu Y, You Q, Zhang X. Li Z, et al. Among authors: su k. J Med Chem. 2020 May 14;63(9):5011. doi: 10.1021/acs.jmedchem.0c00599. Epub 2020 Apr 28. J Med Chem. 2020. PMID: 32343575 No abstract available.

4

The prolyl hydroxylase inhibitor roxadustat: Paradigm in drug discovery and prospects for clinical application beyond anemia.

Su K, Li Z, Yu Y, Zhang X. Su K, et al. Drug Discov Today. 2020 Jul;25(7):1262-1269. doi: 10.1016/j.drudis.2020.04.017. Epub 2020 May 4. Drug Discov Today. 2020. PMID: 32380083

5

A small-molecule probe for monitoring binding to prolyl hydroxylase domain 2 by fluorescence polarisation.

Li Z , Zhen S , Su K , Tumber A , Yu Q , Dong Y , McDonough M , Schofield CJ , Zhang X . Li Z , et al. Among authors: su k. Chem Commun (Camb). 2020 Nov 25;56(91):14199-14202. doi: 10.1039/d0cc06353c. Epub 2020 Oct 28. Chem Commun (Camb). 2020. PMID: 33111730

6

Discovery of a Potent and Orally Bioavailable Hypoxia-Inducible Factor 2α (HIF-2α) Agonist and Its Synergistic Therapy with Prolyl Hydroxylase Inhibitors for the Treatment of Renal Anemia.

Yu Y, Yang F, Yu Q, Liu S, Wu C, Su K, Yang L, Bao X, Li Z, Li X, Zhang X. Yu Y, et al. Among authors: su k. J Med Chem. 2021 Dec 9;64(23):17384-17402. doi: 10.1021/acs.jmedchem.1c01479. Epub 2021 Oct 28. J Med Chem. 2021. PMID: 34709043

7

In Situ Inhibitor Synthesis and Screening by Fluorescence Polarization: An Efficient Approach for Accelerating Drug Discovery.

Li Z, Wu Y, Zhen S, Su K, Zhang L, Yang F, McDonough MA, Schofield CJ, Zhang X. Li Z, et al. Among authors: su k. Angew Chem Int Ed Engl. 2022 Nov 7;61(45):e202211510. doi: 10.1002/anie.202211510. Epub 2022 Oct 11. Angew Chem Int Ed Engl. 2022. PMID: 36112310 Free PMC article.

8

Preferred Conformation-Guided Discovery of Potent and Orally Active HIF Prolyl Hydroxylase 2 Inhibitors for the Treatment of Anemia.

Wu Y, Zhang L, Sun Z, Qiu X, Chen Y, Su K, Yang L, Du Z, Dong Y, Yang F, Li X, Zhang X. Wu Y, et al. Among authors: su k. J Med Chem. 2023 Jul 13;66(13):8545-8563. doi: 10.1021/acs.jmedchem.3c00231. Epub 2023 Jun 27. J Med Chem. 2023. PMID: 37367818

9

Corrigendum to "Tetrahydropyridin-4-ylpicolinoylglycines as novel and orally active prolyl hydroxylase 2 (PHD2) inhibitors for the treatment of renal anemia" [Eur. J. Med. Chem. 238 (2022) 114479].

Su K, Li Z, Zhang L, Fang S, Mao M, Sun Z, Zhang X. Su K, et al. Eur J Med Chem. 2023 Nov 5;259:115692. doi: 10.1016/j.ejmech.2023.115692. Epub 2023 Aug 6. Eur J Med Chem. 2023. PMID: 37550158 No abstract available.

10

In Situ Inhibitor Synthesis and Screening by Fluorescence Polarization: An Efficient Approach for Accelerating Drug Discovery.

Li Z, Wu Y, Zhen S, Su K, Zhang L, Yang F, McDonough MA, Schofield CJ, Zhang X. Li Z, et al. Among authors: su k. Angew Chem Weinheim Bergstr Ger. 2022 Nov 7;134(45):e202211510. doi: 10.1002/ange.202211510. Epub 2022 Oct 10. Angew Chem Weinheim Bergstr Ger. 2022. PMID: 38505687 Free PMC article.

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