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129 results

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Page 1
Design and rationale of GUARDD-US: A pragmatic, randomized trial of genetic testing for APOL1 and pharmacogenomic predictors of antihypertensive efficacy in patients with hypertension.
Eadon MT, Cavanaugh KL, Orlando LA, Christian D, Chakraborty H, Steen-Burrell KA, Merrill P, Seo J, Hauser D, Singh R, Beasley CM, Fuloria J, Kitzman H, Parker AS, Ramos M, Ong HH, Elwood EN, Lynch SE, Clermont S, Cicali EJ, Starostik P, Pratt VM, Nguyen KA, Rosenman MB, Calman NS, Robinson M, Nadkarni GN, Madden EB, Kucher N, Volpi S, Dexter PR, Skaar TC, Johnson JA, Cooper-DeHoff RM, Horowitz CR; GUARDD-US Investigators. Eadon MT, et al. Among authors: lynch se. Contemp Clin Trials. 2022 Aug;119:106813. doi: 10.1016/j.cct.2022.106813. Epub 2022 Jun 1. Contemp Clin Trials. 2022. PMID: 35660539 Free PMC article. Clinical Trial.
Establishing the value of genomics in medicine: the IGNITE Pragmatic Trials Network.
Ginsburg GS, Cavallari LH, Chakraborty H, Cooper-DeHoff RM, Dexter PR, Eadon MT, Ferket BS, Horowitz CR, Johnson JA, Kannry J, Kucher N, Madden EB, Orlando LA, Parker W, Peterson J, Pratt VM, Rakhra-Burris TK, Ramos MA, Skaar TC, Sperber N, Steen-Burrell KA, Van Driest SL, Voora D, Wiisanen K, Winterstein AG, Volpi S; IGNITE PTN. Ginsburg GS, et al. Genet Med. 2021 Jul;23(7):1185-1191. doi: 10.1038/s41436-021-01118-9. Epub 2021 Mar 29. Genet Med. 2021. PMID: 33782552 Free PMC article. Clinical Trial.
Implementing a pragmatic clinical trial to tailor opioids for acute pain on behalf of the IGNITE ADOPT PGx investigators.
Cavallari LH, Cicali E, Wiisanen K, Fillingim RB, Chakraborty H, Myers RA, Blake KV, Asiyanbola B, Baye JF, Bronson WH, Cook KJ, Elwood EN, Gray CF, Gong Y, Hines L, Kannry J, Kucher N, Lynch S, Nguyen KA, Obeng AO, Pratt VM, Prieto HA, Ramos M, Sadeghpour A, Singh R, Rosenman M, Starostik P, Thomas CD, Tillman E, Dexter PR, Horowitz CR, Orlando LA, Peterson JF, Skaar TC, Van Driest SL, Volpi S, Voora D, Parvataneni HK, Johnson JA; IGNITE Pragmatic Trials Network. Cavallari LH, et al. Clin Transl Sci. 2022 Oct;15(10):2479-2492. doi: 10.1111/cts.13376. Epub 2022 Aug 4. Clin Transl Sci. 2022. PMID: 35899435 Free PMC article. Clinical Trial.
Implementing a pragmatic clinical trial to tailor opioids for chronic pain on behalf of the IGNITE ADOPT PGx investigators.
Skaar TC, Myers RA, Fillingim RB, Callaghan JT, Cicali E, Eadon MT, Elwood EN, Ginsburg GS, Lynch S, Nguyen KA, Obeng AO, Park H, Pratt VM, Rosenman M, Sadeghpour A, Shuman S, Singh R, Tillman EM, Volpi S, Wiisanen K, Winterstein AG, Horowitz CR, Voora D, Orlando L, Chakraborty H, Van Driest S, Peterson JF, Cavallari LA, Johnson JA, Dexter PR; IGNITE Pragmatic Trials Network. Skaar TC, et al. Clin Transl Sci. 2024 Aug;17(8):e70005. doi: 10.1111/cts.70005. Clin Transl Sci. 2024. PMID: 39177194 Free PMC article. Clinical Trial.
Development of a Multifaceted Program for Pharmacogenetics Adoption at an Academic Medical Center: Practical Considerations and Lessons Learned.
Shugg T, Tillman EM, Breman AM, Hodge JC, McDonald CA, Ly RC, Rowe EJ, Osei W, Smith TB, Schwartz PH, Callaghan JT, Pratt VM, Lynch S, Eadon MT, Skaar TC. Shugg T, et al. Clin Pharmacol Ther. 2024 Oct;116(4):914-931. doi: 10.1002/cpt.3402. Epub 2024 Aug 21. Clin Pharmacol Ther. 2024. PMID: 39169556 Free PMC article.
Contrasting dynamics of two incursions of low-pathogenicity avian influenza virus into Australia.
Wille M, Broz I, Cherrington T, Crawley A, Farrugia B, Ford M, Frost M, Grimsey J, Kirkland PD, Latimore S, Lynch SE, Martin S, Matereke C, Mee PT, Neave MJ, O'Dea M, Read AJ, O'Riley K, Stevens V, Thayaparan S, Zufan S, Ban de Gouvea Pedroso S, Grillo V, Breed AC, Barr IG, Holmes EC, Klaassen M, Wong FYK. Wille M, et al. Among authors: lynch se. Virus Evol. 2024 Sep 10;10(1):veae076. doi: 10.1093/ve/veae076. eCollection 2024. Virus Evol. 2024. PMID: 39416286 Free PMC article.
Independent repeated mutations within the alphaviruses Ross River virus and Barmah Forest virus indicates convergent evolution and past positive selection in ancestral populations despite ongoing purifying selection.
Pyke AT, Wilson DJ, Michie A, Mackenzie JS, Imrie A, Cameron J, Doggett SL, Haniotis J, Herrero LJ, Caly L, Lynch SE, Mee PT, Madzokere ET, Ramirez AL, Paramitha D, Hobson-Peters J, Smith DW, Weir R, Sullivan M, Druce J, Melville L, Robson J, Gibb R, van den Hurk AF, Duchene S. Pyke AT, et al. Among authors: lynch se. Virus Evol. 2024 Sep 13;10(1):veae080. doi: 10.1093/ve/veae080. eCollection 2024. Virus Evol. 2024. PMID: 39411152 Free PMC article.
PET imaging of [52 Mn]Mn-DOTATATE and [52 Mn]Mn-DOTA-JR11.
Omweri JM, Houson HA, Lynch SE, Tekin V, Sorace AG, Lapi SE. Omweri JM, et al. Among authors: lynch se. Res Sq [Preprint]. 2024 Aug 9:rs.3.rs-4684098. doi: 10.21203/rs.3.rs-4684098/v1. Res Sq. 2024. PMID: 39149492 Free PMC article. Preprint.
129 results