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Androgen signaling in adipose tissue, but less likely skeletal muscle, mediates development of metabolic traits in a PCOS mouse model.
Xiong T, Rodriguez Paris V, Edwards MC, Hu Y, Cochran BJ, Rye KA, Ledger WL, Padmanabhan V, Handelsman DJ, Gilchrist RB, Walters KA. Xiong T, et al. Among authors: handelsman dj. Am J Physiol Endocrinol Metab. 2022 Aug 1;323(2):E145-E158. doi: 10.1152/ajpendo.00418.2021. Epub 2022 Jun 6. Am J Physiol Endocrinol Metab. 2022. PMID: 35658542 Free article.
Female mice haploinsufficient for an inactivated androgen receptor (AR) exhibit age-dependent defects that resemble the AR null phenotype of dysfunctional late follicle development, ovulation, and fertility.
Walters KA, Allan CM, Jimenez M, Lim PR, Davey RA, Zajac JD, Illingworth P, Handelsman DJ. Walters KA, et al. Among authors: handelsman dj. Endocrinology. 2007 Aug;148(8):3674-84. doi: 10.1210/en.2007-0248. Epub 2007 Apr 26. Endocrinology. 2007. PMID: 17463055
Androgen actions and the ovary.
Walters KA, Allan CM, Handelsman DJ. Walters KA, et al. Among authors: handelsman dj. Biol Reprod. 2008 Mar;78(3):380-9. doi: 10.1095/biolreprod.107.064089. Epub 2007 Nov 14. Biol Reprod. 2008. PMID: 18003945 Review.
677 results