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151 results

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Page 1
Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates.
Brown KM, Nair JK, Janas MM, Anglero-Rodriguez YI, Dang LTH, Peng H, Theile CS, Castellanos-Rizaldos E, Brown C, Foster D, Kurz J, Allen J, Maganti R, Li J, Matsuda S, Stricos M, Chickering T, Jung M, Wassarman K, Rollins J, Woods L, Kelin A, Guenther DC, Mobley MW, Petrulis J, McDougall R, Racie T, Bombardier J, Cha D, Agarwal S, Johnson L, Jiang Y, Lentini S, Gilbert J, Nguyen T, Chigas S, LeBlanc S, Poreci U, Kasper A, Rogers AB, Chong S, Davis W, Sutherland JE, Castoreno A, Milstein S, Schlegel MK, Zlatev I, Charisse K, Keating M, Manoharan M, Fitzgerald K, Wu JT, Maier MA, Jadhav V. Brown KM, et al. Among authors: kasper a. Nat Biotechnol. 2022 Oct;40(10):1500-1508. doi: 10.1038/s41587-022-01334-x. Epub 2022 Jun 2. Nat Biotechnol. 2022. PMID: 35654979
High resistance barrier and prophylactic protection in preclinical models of SARS-CoV-2 with two siRNA combination.
Anglero-Rodriguez YI, Lempp FA, Subramanian M, McIninch J, Schlegel MK, Bohan D, Wong E, Brown CR, Foster DJ, Castoreno AB, Nguyen T, Cuffe D, Montiel-Ruiz M, Kaiser H, Sahakyan A, Spreafico R, Morskaya SS, Barry JD, Berman D, Zhang L, Lefebvre S, Kasper A, Racie T, Weddle D, Mobley M, Wassarman K, Bisbe A, Zlatev I, Rogers A, Nechev L, Dybowski J, Chong S, Nair J, Simon A, Sloan K, Hwang S, Virgin HW, Fitzgerald K, Maier MA, Hinkle G, Hebner CM, Akinc A, Jadhav V. Anglero-Rodriguez YI, et al. Among authors: kasper a. Nucleic Acids Res. 2024 Dec 9:gkae1195. doi: 10.1093/nar/gkae1195. Online ahead of print. Nucleic Acids Res. 2024. PMID: 39657790
Blood pressure-independent renoprotective effects of small interference RNA targeting liver angiotensinogen in experimental diabetes.
Cruz-López EO, Ren L, Uijl E, Clahsen-van Groningen MC, van Veghel R, Garrelds IM, Domenig O, Poglitsch M, Zlatev I, Rooney T, Kasper A, Nioi P, Foster D, Danser AHJ. Cruz-López EO, et al. Among authors: kasper a. Br J Pharmacol. 2023 Jan;180(1):80-93. doi: 10.1111/bph.15955. Epub 2022 Oct 2. Br J Pharmacol. 2023. PMID: 36106615 Free PMC article.
Newborn Screening and Presymptomatic Treatment of Metachromatic Leukodystrophy.
Laugwitz L, Mechtler TP, Janzen N, Oliva P, Kasper AR, Teunissen CE, Bürger F, Janda J, Döring M, Weitz M, Lang P, Martin P, Beck-Woedl S, Chanson C, Essing MM, Shenker A, Haack TB, Schulte JH, Rosewich H, Streubel B, Kasper DC, Groeschel S. Laugwitz L, et al. Among authors: kasper ar. N Engl J Med. 2024 Oct 3;391(13):1256-1258. doi: 10.1056/NEJMc2407165. Epub 2024 Sep 18. N Engl J Med. 2024. PMID: 39292923 No abstract available.
151 results