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Potential antigenic explanation for atypical H1N1 infections among middle-aged adults during the 2013-2014 influenza season.
Linderman SL, Chambers BS, Zost SJ, Parkhouse K, Li Y, Herrmann C, Ellebedy AH, Carter DM, Andrews SF, Zheng NY, Huang M, Huang Y, Strauss D, Shaz BH, Hodinka RL, Reyes-Terán G, Ross TM, Wilson PC, Ahmed R, Bloom JD, Hensley SE. Linderman SL, et al. Among authors: hensley se. Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):15798-803. doi: 10.1073/pnas.1409171111. Epub 2014 Oct 20. Proc Natl Acad Sci U S A. 2014. PMID: 25331901 Free PMC article. Clinical Trial.
Contemporary H3N2 influenza viruses have a glycosylation site that alters binding of antibodies elicited by egg-adapted vaccine strains.
Zost SJ, Parkhouse K, Gumina ME, Kim K, Diaz Perez S, Wilson PC, Treanor JJ, Sant AJ, Cobey S, Hensley SE. Zost SJ, et al. Among authors: hensley se. Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12578-12583. doi: 10.1073/pnas.1712377114. Epub 2017 Nov 6. Proc Natl Acad Sci U S A. 2017. PMID: 29109276 Free PMC article.
154 results