Hsiung S - Search Results

1

BCL6-dependent TCF-1⁺ progenitor cells maintain effector and helper CD4⁺ T cell responses to persistent antigen.

Xia Y, Sandor K, Pai JA, Daniel B, Raju S, Wu R, Hsiung S, Qi Y, Yangdon T, Okamoto M, Chou C, Hiam-Galvez KJ, Schreiber RD, Murphy KM, Satpathy AT, Egawa T. Xia Y, et al. Among authors: hsiung s. Immunity. 2022 Jul 12;55(7):1200-1215.e6. doi: 10.1016/j.immuni.2022.05.003. Epub 2022 May 27. Immunity. 2022. PMID: 35637103 Free PMC article.

2

Runx1 and Cbfβ regulate the development of Flt3+ dendritic cell progenitors and restrict myeloproliferative disorder.

Satpathy AT, Briseño CG, Cai X, Michael DG, Chou C, Hsiung S, Bhattacharya D, Speck NA, Egawa T. Satpathy AT, et al. Among authors: hsiung s. Blood. 2014 May 8;123(19):2968-77. doi: 10.1182/blood-2013-11-539643. Epub 2014 Mar 27. Blood. 2014. PMID: 24677539 Free PMC article.

3

Divergent clonal differentiation trajectories of T cell exhaustion.

Daniel B, Yost KE, Hsiung S, Sandor K, Xia Y, Qi Y, Hiam-Galvez KJ, Black M, J Raposo C, Shi Q, Meier SL, Belk JA, Giles JR, Wherry EJ, Chang HY, Egawa T, Satpathy AT. Daniel B, et al. Among authors: hsiung s. Nat Immunol. 2022 Nov;23(11):1614-1627. doi: 10.1038/s41590-022-01337-5. Epub 2022 Oct 26. Nat Immunol. 2022. PMID: 36289450 Free PMC article.

4

Population dynamics and gene regulation of T cells in response to chronic antigen stimulation.

Hsiung S, Egawa T. Hsiung S, et al. Int Immunol. 2023 Feb 11;35(2):67-77. doi: 10.1093/intimm/dxac050. Int Immunol. 2023. PMID: 36334059 Free PMC article. Review.

5

Sustained IL-2R signaling of limited duration by high-dose mIL-2/mCD25 fusion protein amplifies tumor-reactive CD8⁺ T cells to enhance antitumor immunity.

Hernandez R, Toomer KH, Põder J, Santos Savio A, Hsiung S, Malek TR. Hernandez R, et al. Among authors: hsiung s. Cancer Immunol Immunother. 2021 Apr;70(4):909-921. doi: 10.1007/s00262-020-02722-5. Epub 2020 Oct 10. Cancer Immunol Immunother. 2021. PMID: 33037893 Free PMC article.

6

IL-2/CD25: A Long-Acting Fusion Protein That Promotes Immune Tolerance by Selectively Targeting the IL-2 Receptor on Regulatory T Cells.

Ward NC, Yu A, Moro A, Ban Y, Chen X, Hsiung S, Keegan J, Arbanas JM, Loubeau M, Thankappan A, Yamniuk AP, Davis JH, Struthers M, Malek TR. Ward NC, et al. Among authors: hsiung s. J Immunol. 2018 Nov 1;201(9):2579-2592. doi: 10.4049/jimmunol.1800907. Epub 2018 Oct 3. J Immunol. 2018. PMID: 30282751 Free PMC article.

7

Persistent IL-2 Receptor Signaling by IL-2/CD25 Fusion Protein Controls Diabetes in NOD Mice by Multiple Mechanisms.

Ward NC, Lui JB, Hernandez R, Yu L, Struthers M, Xie J, Santos Savio A, Dwyer CJ, Hsiung S, Yu A, Malek TR. Ward NC, et al. Among authors: hsiung s. Diabetes. 2020 Nov;69(11):2400-2413. doi: 10.2337/db20-0186. Epub 2020 Aug 25. Diabetes. 2020. PMID: 32843568 Free PMC article.

8

Acute Lipopolysaccharide-Induced Inflammation Lowers IL-2R Signaling and the Proliferative Potential of Regulatory T Cells.

Hsiung S, Moro A, Ban Y, Chen X, Savio AS, Hernandez R, Malek TR. Hsiung S, et al. Immunohorizons. 2020 Dec 17;4(12):809-824. doi: 10.4049/immunohorizons.2000099. Immunohorizons. 2020. PMID: 33334814 Free article.

9

Dynamic transcriptional activity and chromatin remodeling of regulatory T cells after varied duration of interleukin-2 receptor signaling.

Moro A, Gao Z, Wang L, Yu A, Hsiung S, Ban Y, Yan A, Sologon CM, Chen XS, Malek TR. Moro A, et al. Among authors: hsiung s. Nat Immunol. 2022 May;23(5):802-813. doi: 10.1038/s41590-022-01179-1. Epub 2022 Apr 21. Nat Immunol. 2022. PMID: 35449416 Free PMC article.

10

High-dose IL-2/CD25 fusion protein amplifies vaccine-induced CD4⁺ and CD8⁺ neoantigen-specific T cells to promote antitumor immunity.

Hernandez R, LaPorte KM, Hsiung S, Santos Savio A, Malek TR. Hernandez R, et al. Among authors: hsiung s. J Immunother Cancer. 2021 Sep;9(9):e002865. doi: 10.1136/jitc-2021-002865. J Immunother Cancer. 2021. PMID: 34475132 Free PMC article.

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