Wu L - Search Results

1

Discovery of novel benzofuro[3,2-b]quinoline derivatives as dual CDK2/Topo I inhibitors.

Huang Y, Liu W, Huang S, Li D, Xu C, Jiang X, Liu M, Liu X, Zhu C, Wu L, Chen H, Xu Z, Zhao Q. Huang Y, et al. Among authors: wu l. Bioorg Chem. 2022 Sep;126:105870. doi: 10.1016/j.bioorg.2022.105870. Epub 2022 May 21. Bioorg Chem. 2022. PMID: 35636125

2

Discovery of novel β-carboline derivatives as selective AChE inhibitors with GSK-3β inhibitory property for the treatment of Alzheimer's disease.

Liu W, Liu X, Liu W, Gao Y, Wu L, Huang Y, Chen H, Li D, Zhou L, Wang N, Xu Z, Jiang X, Zhao Q. Liu W, et al. Among authors: wu l. Eur J Med Chem. 2022 Feb 5;229:114095. doi: 10.1016/j.ejmech.2021.114095. Epub 2021 Dec 30. Eur J Med Chem. 2022. PMID: 34995924

3

Design, synthesis, and biological evaluation of β-carboline 1,3,4-oxadiazole based hybrids as HDAC inhibitors with potential antitumor effects.

Tian C, Huang S, Xu Z, Liu W, Li D, Liu M, Zhu C, Wu L, Jiang X, Ding H, Zhao Q. Tian C, et al. Among authors: wu l. Bioorg Med Chem Lett. 2022 May 15;64:128663. doi: 10.1016/j.bmcl.2022.128663. Epub 2022 Mar 7. Bioorg Med Chem Lett. 2022. PMID: 35272009

4

Discovery of novel tacrine derivatives as potent antiproliferative agents with CDKs inhibitory property.

Liu W, Wu L, Li D, Huang Y, Liu M, Liu W, Tian C, Liu X, Jiang X, Hu X, Gao X, Xu Z, Lu H, Zhao Q. Liu W, et al. Among authors: wu l. Bioorg Chem. 2022 Sep;126:105875. doi: 10.1016/j.bioorg.2022.105875. Epub 2022 May 18. Bioorg Chem. 2022. PMID: 35623141

5

Exploration of 4-(1H-indol-3-yl)cyclohex-3-en-1-amine analogues as HDAC inhibitors: Design, synthesis, biological evaluation and modelling studies.

Zhu C, Liu M, Yuan Y, Chen H, Wu L, Cong Z, Zhao Q, Ding H. Zhu C, et al. Among authors: wu l. Bioorg Med Chem Lett. 2022 Sep 15;72:128846. doi: 10.1016/j.bmcl.2022.128846. Epub 2022 Jun 11. Bioorg Med Chem Lett. 2022. PMID: 35697181

6

Design, synthesis and biological evaluation of novel coumarin derivatives as multifunctional ligands for the treatment of Alzheimer's disease.

Liu W, Wu L, Liu W, Tian L, Chen H, Wu Z, Wang N, Liu X, Qiu J, Feng X, Xu Z, Jiang X, Zhao Q. Liu W, et al. Among authors: wu l, wu z. Eur J Med Chem. 2022 Nov 15;242:114689. doi: 10.1016/j.ejmech.2022.114689. Epub 2022 Aug 19. Eur J Med Chem. 2022. PMID: 36007469

7

Development and structure-activity relationship of tacrine derivatives as highly potent CDK2/9 inhibitors for the treatment of cancer.

Wu L, Liu W, Huang Y, Zhu C, Ma Q, Wu Q, Tian L, Feng X, Liu M, Wang N, Xu X, Liu X, Xu C, Qiu J, Xu Z, Liu W, Zhao Q. Wu L, et al. Among authors: wu q. Eur J Med Chem. 2022 Nov 15;242:114701. doi: 10.1016/j.ejmech.2022.114701. Epub 2022 Aug 28. Eur J Med Chem. 2022. PMID: 36054949

8

Discovery of novel β-carboline-1,2,3-triazole hybrids as AChE/GSK-3β dual inhibitors for Alzheimer's disease treatment.

Liu W, Tian L, Wu L, Chen H, Wang N, Liu X, Zhao C, Wu Z, Jiang X, Wu Q, Xu Z, Liu W, Zhao Q. Liu W, et al. Among authors: wu q, wu l, wu z. Bioorg Chem. 2022 Dec;129:106168. doi: 10.1016/j.bioorg.2022.106168. Epub 2022 Sep 28. Bioorg Chem. 2022. PMID: 36191431

9

An inhibitor with GSK3β and DYRK1A dual inhibitory properties reduces Tau hyperphosphorylation and ameliorates disease in models of Alzheimer's disease.

Liu X, Lai LY, Chen JX, Li X, Wang N, Zhou LJ, Jiang XW, Hu XL, Liu WW, Jiao XM, Qi ZT, Liu WJ, Wu LM, Huang YG, Xu ZH, Zhao QC. Liu X, et al. Neuropharmacology. 2023 Jul 1;232:109525. doi: 10.1016/j.neuropharm.2023.109525. Epub 2023 Mar 31. Neuropharmacology. 2023. PMID: 37004752

10

Discovery of novel harmine derivatives as GSK-3β/DYRK1A dual inhibitors for Alzheimer's disease treatment.

Qiu J, Feng X, Chen H, Liu W, Liu W, Wu L, Gao X, Liu Y, Huang Y, Gong H, Qi Y, Xu Z, Zhao Q. Qiu J, et al. Among authors: wu l. Arch Pharm (Weinheim). 2024 Feb;357(2):e2300404. doi: 10.1002/ardp.202300404. Epub 2023 Nov 27. Arch Pharm (Weinheim). 2024. PMID: 38010470

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