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Mechanisms of action of the sodium-glucose cotransporter-2 (SGLT2) inhibitor canagliflozin on tubular inflammation and damage: A post hoc mediation analysis of the CANVAS trial.
Sen T, Koshino A, Neal B, Bijlsma MJ, Arnott C, Li J, Hansen MK, Ix JH, Heerspink HJL. Sen T, et al. Among authors: li j. Diabetes Obes Metab. 2022 Oct;24(10):1950-1956. doi: 10.1111/dom.14779. Epub 2022 Jun 28. Diabetes Obes Metab. 2022. PMID: 35635326 Free PMC article. Clinical Trial.
Evaluating the Effects of Canagliflozin on Cardiovascular and Renal Events in Patients With Type 2 Diabetes Mellitus and Chronic Kidney Disease According to Baseline HbA1c, Including Those With HbA1c <7%: Results From the CREDENCE Trial.
Cannon CP, Perkovic V, Agarwal R, Baldassarre J, Bakris G, Charytan DM, de Zeeuw D, Edwards R, Greene T, Heerspink HJL, Jardine MJ, Levin A, Li JW, Neal B, Pollock C, Wheeler DC, Zhang H, Zinman B, Mahaffey KW. Cannon CP, et al. Among authors: li jw. Circulation. 2020 Feb 4;141(5):407-410. doi: 10.1161/CIRCULATIONAHA.119.044359. Epub 2019 Nov 11. Circulation. 2020. PMID: 31707795 Clinical Trial. No abstract available.
Sodium-glucose co-transporter-2 inhibition and ocular outcomes in patients with type 2 diabetes: A systematic review and meta-analysis.
Li C, Zhou Z, Neuen BL, Yu J, Huang Y, Young T, Li J, Li L, Perkovic V, Jardine MJ, Keay L, Markoulli M, Rosenthal N, Capuano G, Yavin Y, Neal B, Arnott C. Li C, et al. Among authors: li j, li l. Diabetes Obes Metab. 2021 Jan;23(1):252-257. doi: 10.1111/dom.14197. Epub 2020 Oct 13. Diabetes Obes Metab. 2021. PMID: 32954617
An exploration of the heterogeneity in effects of SGLT2 inhibition on cardiovascular and all-cause mortality in the EMPA-REG OUTCOME, CANVAS Program, DECLARE-TIMI 58, and CREDENCE trials.
Yu J, Zhou Z, Mahaffey KW, Matthews DR, Neuen BL, Heerspink HJL, Jardine MJ, Li J, Perkovic V, Neal B, Arnott C. Yu J, et al. Among authors: li j. Int J Cardiol. 2021 Feb 1;324:165-172. doi: 10.1016/j.ijcard.2020.09.050. Epub 2020 Sep 24. Int J Cardiol. 2021. PMID: 32979427
Early Change in Albuminuria with Canagliflozin Predicts Kidney and Cardiovascular Outcomes: A PostHoc Analysis from the CREDENCE Trial.
Oshima M, Neuen BL, Li J, Perkovic V, Charytan DM, de Zeeuw D, Edwards R, Greene T, Levin A, Mahaffey KW, De Nicola L, Pollock C, Rosenthal N, Wheeler DC, Jardine MJ, Heerspink HJL. Oshima M, et al. Among authors: li j. J Am Soc Nephrol. 2020 Dec;31(12):2925-2936. doi: 10.1681/ASN.2020050723. Epub 2020 Sep 30. J Am Soc Nephrol. 2020. PMID: 32998938 Free PMC article. Clinical Trial.
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