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Matrix stiffness mediates pancreatic cancer chemoresistance through induction of exosome hypersecretion in a cancer associated fibroblasts-tumor organoid biomimetic model.
Xiao W, Pahlavanneshan M, Eun CY, Zhang X, DeKalb C, Mahgoub B, Knaneh-Monem H, Shah S, Sohrabi A, Seidlits SK, Hill R. Xiao W, et al. Among authors: mahgoub b. Matrix Biol Plus. 2022 May 16;14:100111. doi: 10.1016/j.mbplus.2022.100111. eCollection 2022 Jun. Matrix Biol Plus. 2022. PMID: 35619988 Free PMC article.
Vendor-specific microbiome controls both acute and chronic murine lung allograft rejection by altering CD4+ Foxp3+ regulatory T cell levels.
Guo Y, Wang Q, Li D, Onyema OO, Mei Z, Manafi A, Banerjee A, Mahgoub B, Stoler MH, Barker TH, Wilkes DS, Gelman AE, Kreisel D, Krupnick AS. Guo Y, et al. Among authors: mahgoub b. Am J Transplant. 2019 Oct;19(10):2705-2718. doi: 10.1111/ajt.15523. Epub 2019 Aug 2. Am J Transplant. 2019. PMID: 31278849 Free PMC article.
Eosinophils downregulate lung alloimmunity by decreasing TCR signal transduction.
Onyema OO, Guo Y, Mahgoub B, Wang Q, Manafi A, Mei Z, Banerjee A, Li D, Stoler MH, Zaidi MT, Schrum AG, Kreisel D, Gelman AE, Jacobsen EA, Krupnick AS. Onyema OO, et al. Among authors: mahgoub b. JCI Insight. 2019 Jun 6;4(11):e128241. doi: 10.1172/jci.insight.128241. eCollection 2019 Jun 6. JCI Insight. 2019. PMID: 31167966 Free PMC article.