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Page 1
Pan-cancer pervasive upregulation of 3' UTR splicing drives tumourigenesis.
Chan JJ, Zhang B, Chew XH, Salhi A, Kwok ZH, Lim CY, Desi N, Subramaniam N, Siemens A, Kinanti T, Ong S, Sanchez-Mejias A, Ly PT, An O, Sundar R, Fan X, Wang S, Siew BE, Lee KC, Chong CS, Lieske B, Cheong WK, Goh Y, Fam WN, Ooi MG, Koh BTH, Iyer SG, Ling WH, Chen J, Yoong BK, Chanwat R, Bonney GK, Goh BKP, Zhai W, Fullwood MJ, Wang W, Tan KK, Chng WJ, Dan YY, Pitt JJ, Roca X, Guccione E, Vardy LA, Chen L, Gao X, Chow PKH, Yang H, Tay Y. Chan JJ, et al. Among authors: desi n. Nat Cell Biol. 2022 Jun;24(6):928-939. doi: 10.1038/s41556-022-00913-z. Epub 2022 May 26. Nat Cell Biol. 2022. PMID: 35618746 Free PMC article.
MiR-138 is a potent regulator of the heterogenous MYC transcript population in cancers.
Desi N, Teh V, Tong QY, Lim CY, Tabatabaeian H, Chew XH, Sanchez-Mejias A, Chan JJ, Zhang B, Pitcheshwar P, Siew BE, Wang S, Lee KC, Chong CS, Cheong WK, Lieske B, Tan IJ, Tan KK, Tay Y. Desi N, et al. Oncogene. 2022 Feb;41(8):1178-1189. doi: 10.1038/s41388-021-02084-x. Epub 2021 Dec 22. Oncogene. 2022. PMID: 34937878 Free PMC article.
Global analysis of RNA-binding proteins identifies a positive feedback loop between LARP1 and MYC that promotes tumorigenesis.
Desi N, Tong QY, Teh V, Chan JJ, Zhang B, Tabatabaeian H, Tan HQ, Kapeli K, Jin W, Lim CY, Kwok ZH, Tan HT, Wang S, Siew BE, Lee KC, Chong CS, Tan KK, Yang H, Kappei D, Yeo GW, Chung MCM, Tay Y. Desi N, et al. Cell Mol Life Sci. 2022 Feb 23;79(3):147. doi: 10.1007/s00018-021-04093-1. Cell Mol Life Sci. 2022. PMID: 35195778 Free PMC article.