Chen Y - Search Results

1

Aberrant methylmalonylation underlies methylmalonic acidemia and is attenuated by an engineered sirtuin.

Head PE, Myung S, Chen Y, Schneller JL, Wang C, Duncan N, Hoffman P, Chang D, Gebremariam A, Gucek M, Manoli I, Venditti CP. Head PE, et al. Among authors: chen y. Sci Transl Med. 2022 May 25;14(646):eabn4772. doi: 10.1126/scitranslmed.abn4772. Epub 2022 May 25. Sci Transl Med. 2022. PMID: 35613279 Free PMC article.

2

The mitochondrial outer membrane protein MDI promotes local protein synthesis and mtDNA replication.

Zhang Y, Chen Y, Gucek M, Xu H. Zhang Y, et al. Among authors: chen y. EMBO J. 2016 May 17;35(10):1045-57. doi: 10.15252/embj.201592994. Epub 2016 Apr 6. EMBO J. 2016. PMID: 27053724 Free PMC article.

3

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB.

Martina JA, Chen Y, Gucek M, Puertollano R. Martina JA, et al. Among authors: chen y. Autophagy. 2012 Jun;8(6):903-14. doi: 10.4161/auto.19653. Epub 2012 May 11. Autophagy. 2012. PMID: 22576015 Free PMC article.

4

Characterization of the cardiac succinylome and its role in ischemia-reperfusion injury.

Boylston JA, Sun J, Chen Y, Gucek M, Sack MN, Murphy E. Boylston JA, et al. Among authors: chen y. J Mol Cell Cardiol. 2015 Nov;88:73-81. doi: 10.1016/j.yjmcc.2015.09.005. Epub 2015 Sep 24. J Mol Cell Cardiol. 2015. PMID: 26388266 Free PMC article.

5

PINK1 Inhibits Local Protein Synthesis to Limit Transmission of Deleterious Mitochondrial DNA Mutations.

Zhang Y, Wang ZH, Liu Y, Chen Y, Sun N, Gucek M, Zhang F, Xu H. Zhang Y, et al. Among authors: chen y. Mol Cell. 2019 Mar 21;73(6):1127-1137.e5. doi: 10.1016/j.molcel.2019.01.013. Epub 2019 Feb 13. Mol Cell. 2019. PMID: 30772175 Free PMC article.

6

Mitochondrial General Control of Amino Acid Synthesis 5 Like 1 Regulates Glutaminolysis, Mammalian Target of Rapamycin Complex 1 Activity, and Murine Liver Regeneration.

Wang L, Zhu L, Wu K, Chen Y, Lee DY, Gucek M, Sack MN. Wang L, et al. Among authors: chen y. Hepatology. 2020 Feb;71(2):643-657. doi: 10.1002/hep.30876. Epub 2019 Oct 17. Hepatology. 2020. PMID: 31344750 Free PMC article.

7

Generation of a mitochondrial protein compendium in Dictyostelium discoideum.

Freitas AV, Herb JT, Pan M, Chen Y, Gucek M, Jin T, Xu H. Freitas AV, et al. Among authors: chen y. iScience. 2022 Apr 29;25(5):104332. doi: 10.1016/j.isci.2022.104332. eCollection 2022 May 20. iScience. 2022. PMID: 35602934 Free PMC article.

8

Metabolic sensor AMPK directly phosphorylates RAG1 protein and regulates V(D)J recombination.

Um JH, Brown AL, Singh SK, Chen Y, Gucek M, Lee BS, Luckey MA, Kim MK, Park JH, Sleckman BP, Gellert M, Chung JH. Um JH, et al. Among authors: chen y. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9873-8. doi: 10.1073/pnas.1307928110. Epub 2013 May 28. Proc Natl Acad Sci U S A. 2013. PMID: 23716691 Free PMC article.

9

Cyclophilin D modulates mitochondrial acetylome.

Nguyen TT, Wong R, Menazza S, Sun J, Chen Y, Wang G, Gucek M, Steenbergen C, Sack MN, Murphy E. Nguyen TT, et al. Among authors: chen y. Circ Res. 2013 Dec 6;113(12):1308-19. doi: 10.1161/CIRCRESAHA.113.301867. Epub 2013 Sep 23. Circ Res. 2013. PMID: 24062335 Free PMC article.

10

Prolonged fasting identifies heat shock protein 10 as a Sirtuin 3 substrate: elucidating a new mechanism linking mitochondrial protein acetylation to fatty acid oxidation enzyme folding and function.

Lu Z, Chen Y, Aponte AM, Battaglia V, Gucek M, Sack MN. Lu Z, et al. Among authors: chen y. J Biol Chem. 2015 Jan 23;290(4):2466-76. doi: 10.1074/jbc.M114.606228. Epub 2014 Dec 12. J Biol Chem. 2015. PMID: 25505263 Free PMC article.

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