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Extracellular vimentin mimics VEGF and is a target for anti-angiogenic immunotherapy.
van Beijnum JR, Huijbers EJM, van Loon K, Blanas A, Akbari P, Roos A, Wong TJ, Denisov SS, Hackeng TM, Jimenez CR, Nowak-Sliwinska P, Griffioen AW. van Beijnum JR, et al. Among authors: jimenez cr. Nat Commun. 2022 May 23;13(1):2842. doi: 10.1038/s41467-022-30063-7. Nat Commun. 2022. PMID: 35606362 Free PMC article.
Exploration of the platelet proteome in patients with early-stage cancer.
Sabrkhany S, Kuijpers MJE, Knol JC, Olde Damink SWM, Dingemans AC, Verheul HM, Piersma SR, Pham TV, Griffioen AW, Oude Egbrink MGA, Jimenez CR. Sabrkhany S, et al. Among authors: jimenez cr. J Proteomics. 2018 Apr 15;177:65-74. doi: 10.1016/j.jprot.2018.02.011. Epub 2018 Feb 10. J Proteomics. 2018. PMID: 29432918 Free article.
Integrating Phenotypic Search and Phosphoproteomic Profiling of Active Kinases for Optimization of Drug Mixtures for RCC Treatment.
van Beijnum JR, Weiss A, Berndsen RH, Wong TJ, Reckman LC, Piersma SR, Zoetemelk M, de Haas R, Dormond O, Bex A, Henneman AA, Jimenez CR, Griffioen AW, Nowak-Sliwinska P. van Beijnum JR, et al. Among authors: jimenez cr. Cancers (Basel). 2020 Sep 21;12(9):2697. doi: 10.3390/cancers12092697. Cancers (Basel). 2020. PMID: 32967224 Free PMC article.
Optimized low-dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment.
Zoetemelk M, Ramzy GM, Rausch M, Koessler T, van Beijnum JR, Weiss A, Mieville V, Piersma SR, de Haas RR, Delucinge-Vivier C, Andres A, Toso C, Henneman AA, Ragusa S, Petrova TV, Docquier M, McKee TA, Jimenez CR, Daali Y, Griffioen AW, Rubbia-Brandt L, Dietrich PY, Nowak-Sliwinska P. Zoetemelk M, et al. Among authors: jimenez cr. Mol Oncol. 2020 Nov;14(11):2894-2919. doi: 10.1002/1878-0261.12797. Epub 2020 Oct 5. Mol Oncol. 2020. PMID: 33021054 Free PMC article.
Effects of Cancer Presence and Therapy on the Platelet Proteome.
Walraven M, Sabrkhany S, Knol JC, Dekker H, de Reus I, Piersma SR, Pham TV, Griffioen AW, Broxterman HJ, Oude Egbrink M, Verheul HMW, Jimenez CR. Walraven M, et al. Among authors: jimenez cr. Int J Mol Sci. 2021 Jul 30;22(15):8236. doi: 10.3390/ijms22158236. Int J Mol Sci. 2021. PMID: 34361002 Free PMC article.
Truncated FGFR2 is a clinically actionable oncogene in multiple cancers.
Zingg D, Bhin J, Yemelyanenko J, Kas SM, Rolfs F, Lutz C, Lee JK, Klarenbeek S, Silverman IM, Annunziato S, Chan CS, Piersma SR, Eijkman T, Badoux M, Gogola E, Siteur B, Sprengers J, de Klein B, de Goeij-de Haas RR, Riedlinger GM, Ke H, Madison R, Drenth AP, van der Burg E, Schut E, Henneman L, van Miltenburg MH, Proost N, Zhen H, Wientjens E, de Bruijn R, de Ruiter JR, Boon U, de Korte-Grimmerink R, van Gerwen B, Féliz L, Abou-Alfa GK, Ross JS, van de Ven M, Rottenberg S, Cuppen E, Chessex AV, Ali SM, Burn TC, Jimenez CR, Ganesan S, Wessels LFA, Jonkers J. Zingg D, et al. Among authors: jimenez cr. Nature. 2022 Aug;608(7923):609-617. doi: 10.1038/s41586-022-05066-5. Epub 2022 Aug 10. Nature. 2022. PMID: 35948633 Free PMC article. Clinical Trial.
Standardization and harmonization of distributed multi-center proteotype analysis supporting precision medicine studies.
Xuan Y, Bateman NW, Gallien S, Goetze S, Zhou Y, Navarro P, Hu M, Parikh N, Hood BL, Conrads KA, Loosse C, Kitata RB, Piersma SR, Chiasserini D, Zhu H, Hou G, Tahir M, Macklin A, Khoo A, Sun X, Crossett B, Sickmann A, Chen YJ, Jimenez CR, Zhou H, Liu S, Larsen MR, Kislinger T, Chen Z, Parker BL, Cordwell SJ, Wollscheid B, Conrads TP. Xuan Y, et al. Among authors: jimenez cr. Nat Commun. 2020 Oct 16;11(1):5248. doi: 10.1038/s41467-020-18904-9. Nat Commun. 2020. PMID: 33067419 Free PMC article.
264 results