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Genome mining, isolation, chemical synthesis and biological evaluation of a novel lanthipeptide, tikitericin, from the extremophilic microorganism Thermogemmatispora strain T81.
Xu B, Aitken EJ, Baker BP, Turner CA, Harvey JE, Stott MB, Power JF, Harris PWR, Keyzers RA, Brimble MA. Xu B, et al. Among authors: keyzers ra. Chem Sci. 2018 Aug 20;9(37):7311-7317. doi: 10.1039/c8sc02170h. eCollection 2018 Oct 7. Chem Sci. 2018. PMID: 30294420 Free PMC article.
Hydrated Rubrolides from the New Zealand Tunicate Synoicum kuranui.
Bracegirdle J, Stevenson LJ, Sharrock AV, Page MJ, Vorster JA, Owen JG, Ackerley DF, Keyzers RA. Bracegirdle J, et al. Among authors: keyzers ra. J Nat Prod. 2021 Feb 26;84(2):544-547. doi: 10.1021/acs.jnatprod.0c01248. Epub 2021 Jan 26. J Nat Prod. 2021. PMID: 33496582
Natural and Semisynthetic Immunomodulatory Luakuliide Labdane Diterpenoids.
Ramirez-Garcia JL, Grant EK, Salamat A, Anker MD, Cameron SA, Kelly M, Matoto SV, Barber JM, Northcote PT, Williams-Spence JW, La Flamme AC, Harvey JE, Singh AJ, Keyzers RA. Ramirez-Garcia JL, et al. Among authors: keyzers ra. J Nat Prod. 2025 Jan 24;88(1):162-174. doi: 10.1021/acs.jnatprod.4c01218. Epub 2024 Dec 23. J Nat Prod. 2025. PMID: 39714955
Four-electron reduction of benzene by a samarium(II)-alkyl without the addition of external reducing agents.
Richardson GM, Rajeshkumar T, Burke FM, Cameron SA, Nicholls BD, Harvey JE, Keyzers RA, Butler T, Granville S, Liu L, Langley J, Lim LF, Cox N, Chilton NF, Hicks J, Davis NJLK, Maron L, Anker MD. Richardson GM, et al. Among authors: keyzers ra. Nat Chem. 2025 Jan;17(1):20-28. doi: 10.1038/s41557-024-01688-6. Epub 2025 Jan 3. Nat Chem. 2025. PMID: 39754016
Enhanced disease reduction using clozapine, an atypical antipsychotic agent, and glatiramer acetate combination therapy in experimental autoimmune encephalomyelitis.
Green LK, Zareie P, Templeton N, Keyzers RA, Connor B, La Flamme AC. Green LK, et al. Among authors: keyzers ra. Mult Scler J Exp Transl Clin. 2017 Mar 17;3(1):2055217317698724. doi: 10.1177/2055217317698724. eCollection 2017 Jan-Mar. Mult Scler J Exp Transl Clin. 2017. PMID: 28607752 Free PMC article.
86 results