Eggers R - Search Results

1

Characterization of an immune-evading doxycycline-inducible lentiviral vector for gene therapy in the spinal cord.

De Winter F, Quijorna IF, Burnside E, Hobo B, Eggers R, Hoyng SA, Mulder HP, Hoeben RC, Muir EM, Bradbury EJ, Verhaagen J. De Winter F, et al. Among authors: eggers r. Exp Neurol. 2022 Sep;355:114120. doi: 10.1016/j.expneurol.2022.114120. Epub 2022 May 20. Exp Neurol. 2022. PMID: 35605669 Free article.

2

Lentiviral vector-mediated reporter gene expression in avulsed spinal ventral root is short-term, but is prolonged using an immune "stealth" transgene.

Hendriks WT, Eggers R, Carlstedt TP, Zaldumbide A, Tannemaat MR, Fallaux FJ, Hoeben RC, Boer GJ, Verhaagen J. Hendriks WT, et al. Among authors: eggers r. Restor Neurol Neurosci. 2007;25(5-6):585-99. Restor Neurol Neurosci. 2007. PMID: 18418947

3

Timed GDNF gene therapy using an immune-evasive gene switch promotes long distance axon regeneration.

Eggers R, de Winter F, Hoyng SA, Hoeben RC, Malessy MJA, Tannemaat MR, Verhaagen J. Eggers R, et al. Brain. 2019 Feb 1;142(2):295-311. doi: 10.1093/brain/awy340. Brain. 2019. PMID: 30649249

4

Enhanced regeneration and reinnervation following timed GDNF gene therapy in a cervical ventral root avulsion.

Eggers R, de Winter F, Arkenaar C, Tannemaat MR, Verhaagen J. Eggers R, et al. Exp Neurol. 2019 Nov;321:113037. doi: 10.1016/j.expneurol.2019.113037. Epub 2019 Aug 16. Exp Neurol. 2019. PMID: 31425689

5

Developing a potentially immunologically inert tetracycline-regulatable viral vector for gene therapy in the peripheral nerve.

Hoyng SA, Gnavi S, de Winter F, Eggers R, Ozawa T, Zaldumbide A, Hoeben RC, Malessy MJ, Verhaagen J. Hoyng SA, et al. Among authors: eggers r. Gene Ther. 2014 Jun;21(6):549-57. doi: 10.1038/gt.2014.22. Epub 2014 Apr 3. Gene Ther. 2014. PMID: 24694534

6

Rescue and sprouting of motoneurons following ventral root avulsion and reimplantation combined with intraspinal adeno-associated viral vector-mediated expression of glial cell line-derived neurotrophic factor or brain-derived neurotrophic factor.

Blits B, Carlstedt TP, Ruitenberg MJ, de Winter F, Hermens WT, Dijkhuizen PA, Claasens JW, Eggers R, van der Sluis R, Tenenbaum L, Boer GJ, Verhaagen J. Blits B, et al. Among authors: eggers r. Exp Neurol. 2004 Oct;189(2):303-16. doi: 10.1016/j.expneurol.2004.05.014. Exp Neurol. 2004. PMID: 15380481

7

Gene therapy approaches to enhance regeneration of the injured peripheral nerve.

de Winter F, Hoyng S, Tannemaat M, Eggers R, Mason M, Malessy M, Verhaagen J. de Winter F, et al. Among authors: eggers r. Eur J Pharmacol. 2013 Nov 5;719(1-3):145-152. doi: 10.1016/j.ejphar.2013.04.057. Epub 2013 Jul 18. Eur J Pharmacol. 2013. PMID: 23872403 Review.

8

Lentiviral vector-mediated gradients of GDNF in the injured peripheral nerve: effects on nerve coil formation, Schwann cell maturation and myelination.

Eggers R, de Winter F, Hoyng SA, Roet KC, Ehlert EM, Malessy MJ, Verhaagen J, Tannemaat MR. Eggers R, et al. PLoS One. 2013 Aug 12;8(8):e71076. doi: 10.1371/journal.pone.0071076. eCollection 2013. PLoS One. 2013. PMID: 23951085 Free PMC article.

9

Combining timed GDNF and ChABC gene therapy to promote long-distance regeneration following ventral root avulsion and repair.

Eggers R, de Winter F, Smit L, Luimens M, Muir EM, Bradbury EJ, Tannemaat MR, Verhaagen J. Eggers R, et al. FASEB J. 2020 Aug;34(8):10605-10622. doi: 10.1096/fj.202000559R. Epub 2020 Jun 16. FASEB J. 2020. PMID: 32543730

10

Gene transfer to the spinal cord neural scar with lentiviral vectors: predominant transgene expression in astrocytes but not in meningeal cells.

Hendriks WT, Eggers R, Verhaagen J, Boer GJ. Hendriks WT, et al. Among authors: eggers r. J Neurosci Res. 2007 Nov 1;85(14):3041-52. doi: 10.1002/jnr.21432. J Neurosci Res. 2007. PMID: 17671987

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